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Aqueous Oldenlandia diffusa extracts inhibits colorectal cancer cells via activating AMP-activated protein kinase signalings

2016

Pei-Hua Lu Min-Bin Chen Chao Ji Wen-Ting Li Mu-Xin Wei Mian-Hua Wu

Here we evaluated the anti-cancer activity of aqueous Oldenlandia diffusa (OD) extracts (ODE) in colorectal cancer (CRC) cells. We showed that ODE exerted potent anti-proliferative, cytotoxic and pro-apoptotic activities against a panel of established CRC lines (HCT-116, DLD-1, HT-29 and Lovo) and primary (patient-derived) human CRC cells. ODE activated AMP-activated protein kinase (AMPK) signa...

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2013

Xin Chen

Hybrid systems are dynamical systems which exhibit both continuous flow and discrete jumps. They are natural modeling formalism for the systems composed of a discrete controller interacting with a physical environment. Since hybrid systems often appear in safetycritical situations, it is non-trivial to study their behavior. A typical way to do that is to explore the reachable state space of a h...

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Aqueous Oldenlandia diffusa extracts inhibits colorectal cancer cells via activating AMP-activated protein kinase signalings

Model file Model parser TM integrator Poly ODE 1 Poly ODE 2 Nonpoly ODE

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