The human growth hormone (hGH) gene is controlled by a long-range enhancer, HSI, located 14.5 kb 5' to the hGH promoter. HSI establishes a domain of noncoding transcription that is 'looped' to the hGH promoter as an essential step in initiating hGH gene expression. Thus, defining how HSI generates its domain of noncoding transcription is central to understanding its long-range function. Here, w...

The purpose of this study was to examine the relationship between osmolality and efferent sympathetic outflow in humans. We hypothesized that increased plasma osmolality would be associated with increases in directly measured sympathetic outflow. Muscle sympathetic outflow was successfully recorded in eight healthy subjects during a 60-min intravenous hypertonic saline infusion (HSI; 3% NaCl) o...

Hyperspectral imagery (HSI) unmixing is a process that decomposes pixel spectra into a collection of constituent spectra (endmembers) and their correspondent abundance fractions. Without knowing any knowledge of HSI data, the unmixing problem is transformed into a blind source separation (BSS) problem. Several methods have been proposed to deal with the problem, like independent component analy...

Hyperspectral imagery (HSI) typically provides a wealth of information captured in a wide range of the electromagnetic spectrum for each pixel in the image. Hence, a pixel in HSI is a high-dimensional vector of intensities with a large spectral range and a high spectral resolution. Therefore, the semantic interpretation is a challenging task of HSI analysis. We focused in this paper on object c...

A number of different interaction modalities have been proposed for human engagement with networked systems. In this paper, we establish formal guarantees for whether or not a given such human-swarm interaction (HSI) strategy is appropriate for achieving particular multi-robot tasks, such as guiding a swarm of robots into a particular geometric configuration. In doing so, we define what it mean...

PROBLEM/CONDITION Heat stress illness (HSI), also known as heat-related illness, comprises mild heat edema, heat syncope, heat cramps, heat exhaustion (the most common type of HSI), and heat stroke (the most severe form). CDC's Environmental Public Health Tracking Program receives annual hospitalization discharge data from 23 states that are used to assess and monitor trends of HSI hospitalizat...

Form Approved OMB No. 0704-0188 Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this burden estimate or any other aspect of this coll...

Displaying the large number of bands in a hyperspectral image (HSI) on a trichromatic monitor is important for HSI processing and analysis system. The visualized image shall convey as much information as possible from the original HSI and meanwhile facilitate image interpretation. However, most existing methods display HSIs in false color, which contradicts with user experience and expectation....

This paper introduces the concept and principles of hyperspectral imaging (HSI) and it briefly outlines how the defence and homeland security sectors can benefit from the application of this extremely versatile technology. This paper outlines the pros and cons of the various HSI system configurations, with particular emphasis on two of the most commonly deployed spectrograph techniques, namely,...