BACKGROUND Several clinical measures of sensory and motor function are used alongside patient-rated questionnaires to assess outcomes of carpal tunnel decompression. However there is a lack of evidence regarding which clinical tests are most responsive to clinically important change over time. METHODS In a prospective cohort study 63 patients undergoing carpal tunnel decompression were assess...

The neuronal mechanisms involved in brain plasticity after skilled motor learning are not completely understood. We aimed to study the short-term effects of keyboard training in music-naive subjects on the motor/premotor cortex activity and interhemispheric interactions, using electroencephalography and transcranial magnetic stimulation (TMS). Twelve subjects (experimental group) underwent, bef...

The main purpose of electroencephalography (EEG)-based brain-computer interface (BCI) technology is to provide an alternative channel to support communication and control when motor pathways are interrupted. Despite the considerable amount of research focused on the improvement of EEG signal detection and translation into output commands, little is known about how learning to operate a BCI devi...

Single pulse transcranial magnetic stimulation (TMS) was used to test the assumption that kinesthetic imagery of action is more 'motor' than visual imagery of action. We assessed corticospinal excitability during motor imagery of a thumb-palm opposition movement by recording potentials evoked by TMS from two hand muscles that would (opponens pollicis, OP, target) or would not (abductor digiti m...

Although facilitation of the corticospinal system during action observation is widely accepted, it remains controversial whether this facilitation reflects a replica of the observed movements or the goal of the observed motor acts. In the present study, we asked whether, when an object is grasped by using a tool, corticospinal facilitation represents 1) the movements of the hand, 2) the movemen...