BACKGROUND Eukaryotic DNA polymerase β (pol β), the polymerase thought to be responsible for DNA repair synthesis, has been extensively characterized in rats and humans. However, pol β has not been purified or enzymatically characterized from the model fish species Danio rerio (zebrafish). We used the in vitro/in vivo dual expression system plasmid, pIVEX, to express Danio rerio pol β (Danio po...

Individual zebrafish Danio rerio were assayed for exploratory tendency in a serial open field test before and after being maintained on one of four diet treatments that differed in ration and in predictability of food delivery. Danio rerio became more exploratory after being maintained on a diet with a predictable delivery schedule. There was no effect of ration. Thus, exploratory behaviour is ...

In this study, we evaluated the bioaccumulation of mercury in zebrafish (Danio rerio) exposed to mercury-contaminated food for 21 days and depuration a subsequent post-exposure period 28 days. Four tissues (muscle, liver, gills, skin) were analyzed content. Overall, data indicated that Hg accumulation liver is faster than other tissues. Furthermore, tissue with highest rate per day (0.021 µg g−...

AGAT, GAMT and CT1, three creatine synthesis and transport-related molecules, have been widely studied in mammals. To explore their homologous genes in adult zebrafish Danio rerio, the gene expression patterns of these three genes in D. rerio were investigated. The results reveal that AGAT, GAMT and CT1 are expressed widely in diverse tissues of D. rerio where the homologous genes in mammals ar...

The zebrafish has long been a favourite model for the study of vertebrate development. Here we provide an overview of the current state of knowledge and resources for the study of this fish, with comments on the future direction of zebrafish genomics from Professor Mark Fishman and Dr Stephen Wilson.

The aim of this study was to investigate effects of subchronic exposure to sublethal levels of diclofenac on growth, oxidative stress, and histopathological changes in Danio rerio. The juvenile growth tests were performed on Danio rerio according to OECD method number 215. Fish at the age of 20 days were exposed to the diclofenac environmental concentration commonly detected in the Czech rivers...

Here, we report the draft genome sequence of Pseudomonas sp. strain DrBHI1. The total assembly length is 5,649,751 bp in 146 contigs. This strain was isolated from zebrafish (Danio rerio) feces.

Graptophyllum pictum is a medicinal plant that helps to cure different forms of disease due the availability beneficial phytochemicals such as flavonoids, steroids, alkaloids, saponins and glycosides. The purpose this research was evaluate toxicity effect G. extract on zebrafish embryos (Danio rerio) at concentrations. extracted using ethanol method.