It is known that curvature relation plays a key role in the propagation of two-dimensional waves in an excitable model. Such a relation is believed to obey the eikonal equation for typical excitable models (e.g., the FitzHugh-Nagumo (FHN) model), which states that the relation between the normal velocity and the local curvature is approximately linear. In this paper, we show that for a simplifi...

BACKGROUND Primary care reform in Ontario, Canada started with the introduction of new enrollment models, the two largest of which are Family Health Networks (FHNs), a capitation-based model, and Family Health Groups (FHGs), a blended fee-for-service model. The purpose of this study was to evaluate differences in performance between FHNs and FHGs and to compare performance before and after phys...

<p style='text-indent:20px;'>In this work we study the synchronization of ring-structured cellular neural networks modeled by lattice FitzHugh-Nagumo equations with boundary feedback. Through uniform estimates solutions and analysis dissipative dynamics, type is proved under condition that gap signal exceeds adjustable threshold.</p>

Scotland has led enactment of the new World Health Organisation (Europe) Family Health Nurse (FHN) concept. This paper presents research which evaluated the initial operation and impact of the role in remote and rural regions of Scotland. Through use of a multiplex research design informed by ideas from realistic evaluation, fourth generation evaluation and case study research, an initial typol...

A general Bayesian framework is introduced for the inference of time-varying parameters in nonstationary, nonlinear, stochastic dynamical systems. Its convergence is discussed. The performance of the method is analyzed in the context of detecting signaling in a system of neurons modeled as FitzHugh-Nagumo (FHN) oscillators. It is assumed that only fast action potentials for each oscillator mixe...

BACKGROUND Even in the absence of heavy alcohol use, youth with familial alcoholism (family history positive [FHP]) exhibit atypical brain functioning and behavior. Although emotional and cognitive systems are affected in alcohol use disorders (AUDs), little attention has focused on whether brain and behavior phenotypes related to the interplay between affective and executive functioning may be...

BACKGROUND Individuals with a positive family history for alcoholism (FHP) have shown differences from family-history-negative (FHN) individuals in the neural correlates of reward processing. FHP, compared to FHN individuals, demonstrate relatively diminished ventral striatal activation during anticipation of monetary rewards, and the degree of ventral striatal activation shows an inverse corre...

Chaos is an important applied area in nonlinear dynamical systems and it is applicable to many real-world systems including the biological systems. Nerve membranes are known to exhibit their own nonlinear dynamics which generate and propagate action potentials. Such nonlinear dynamics in nerve membranes can produce chaos in neurons and related bifurcations. In 1952, A.L. Hodgkin and A.F. Huxley...

The treatment of osteonecrosis of the femoral head (FHN) is controversial. It mainly occurs in young patients in whom total hip replacement is best avoided because of an increased risk of revision. The objective of this long-term follow-up study was to evaluate the outcome of intertrochanteric flexion osteotomy as a hip joint preserving operation for FHN. Over a 19-year period we carried out 70...

BACKGROUND The development of alcohol use disorders is genetically influenced, and may be mediated through differences in the subjective response to alcohol. There is some evidence to suggest that response differences to alcohol could be conveyed by heritable differences in GABAA receptors. The purpose of this study was to investigate whether individuals with a family history positive (FHP) for...