Quadratic inference functions (QIF) methodology is an important alternative to the generalized estimating equations (GEE) method in the longitudinal marginal model, as it offers higher estimation efficiency than the GEE when correlation structure is misspecified. The focus of this paper is on sample size determination and power calculation for QIF based on the Wald test in a marginal logistic m...

Generalized estimating equations (GEE) are commonly used for the analysis of correlated data. However, use of quadratic inference functions (QIFs) is becoming popular because it increases efficiency relative to GEE when the working covariance structure is misspecified. Although shown to be advantageous in the literature, the impacts of covariates and imbalanced cluster sizes on the estimation p...

Estimation in binary longitudinal data by using generalized estimating equation (GEE) becomes complicated in the presence of missing data because standard GEEs are only valid under the restrictive missing completely at random assumption. Weighted GEE has therefore been proposed to allow the validity of GEE's under the weaker missing at random assumption. Multiple imputation offers an attractive...

conclusions according to the findings of this study, there is no relationship between shift work and changes in serum tg and cholesterol. the lack of relationship can be due to shift plans for shift workers, nutrition, or the “healthy heart project” at isfahan mobarakeh steel company. results the results showed a significant difference in cholesterol levels between shift workers and day workers...

This paper presents a pseudo-GEE approach to the analysis of longitudinal surveys when the response variable contains missing values. A cycle-specific marginal hotdeck imputation method is proposed to fill in the missing responses and the pseudo-GEE method described in Carrillo et al. (2009) is applied to the imputed data set. Consistency of the resulting pseudo-GEE estimators is established un...

Parkinson's disease (PD) is associated with loss of total glutathione (GSH) which may contribute to progressive cell death. Peripheral GSH administration has been used clinically with reported benefits. Despite this, there is little specific information to characterize its cellular uptake or clearance, brain elevation with peripheral delivery or neuroprotective efficacy in PD models. The curren...

The most commonly used model selection criterion, Akaike’s Information Criterion (AIC), cannot be used when the Generalized Estimating Equations (GEE) approach is considered for analyzing multivariate binary response. Recently, a modified version of AIC (mAIC) which is based on quasi-likelihood function is proposed as a model selection criterion. This model selection criterion can be used in th...

The Generalised Estimating Equations (GEE) proposed by Liang and Zeger (1986) and Zeger and Liang (1986) have found considerable attention in the last ten years and several extensions have been proposed. In this annotated bibliography we describe the development of the GEE and its extensions during the last decade. Additionally, we discuss advantages and disadvantages of the different parametri...

Correlated response data are common in biomedical studies. Regression analysis based on the generalized estimating equations (GEE) is an increasingly important method for such data. However, there seem to be few model-selection criteria available in GEE. The well-known Akaike Information Criterion (AIC) cannot be directly applied since AIC is based on maximum likelihood estimation while GEE is ...