An interest rate swap is a contract between two parties to exchange periodically fixed rate payments for floating rate payments based on an agreed-upon notional principal and maturity. The fixed rate is known as the swap rate and a swap curve can be constructed using swap rates of different maturities. The swap curve is widely used by financial market participants as the benchmark for the prici...

Spontaneous maturation observed in dendritic cell (DC) cultures has been linked to their capacity to induce immune responses. Despite several recent studies, the mechanisms and signals triggering spontaneous maturation of DCs are largely unknown. We found that the absence of SWAP-70 causes spontaneous maturation of spleen- and bone marrow-derived DCs and, in vivo, of spleen-resident CD11c(+)CD1...

In this paper we introduce the notion of best swap for a failing edge of a single source shortest paths tree (SPT) S(r) rooted in r in a weighted graph G = (V, E). Given an edge e ∈ S(r), an edge e′ ∈ E \{e} is a swap edge if the swap tree Se/e′(r) obtained by swapping e with e′ in S(r) is a spanning tree of G. A best swap edge for a given edge e is a swap edge minimizing some distance function...

SWAP-70, a phosphatidylinositol trisphosphate (PtdIns(3,4,5)P(3)) binding protein, has been suggested to be involved in transformation of mouse embryo fibroblasts (MEFs) as well as membrane ruffling after growth factor stimulation of the cells. A mutant, SWAP-70-374, was found to be able to bind to F-actin in vitro, whereas wild-type SWAP-70 failed to do so. This mutant was present at the plasm...

Clustering is an unsupervised learning method widely used in many fields, such as machine learning, pattern recognition, data mining and image analysis. The goal of this study is to investigate swap-based clustering and its application to location-based services. Swap-based clustering is a local search heuristic trying to find the optimal centroid locations by performing a sequence of centroid ...

This paper examines the causal relationship between euro and sterling swap spreads during the period January, 1999 to March, 2003. The absence of any correlation between changes in the two swap spreads would indicate that credit risk factors are country-specific. But euro swap spreads showed some correlation with the interest rate differentials between the two markets. Both spreads follow a GAR...

SWAP-70 is a protein that has been suggested to be involved in regulation of actin rearrangement. Having discovered that an artificially-derived mutant of SWAP-70 can transform mouse embryo fibroblasts, we searched for naturally-occurring mutations in the SWAP-70 gene, finding listings for several on the Web at www.sanger.ac.uk/genetics/CGP/cosmic/, including three mutations found in ovarian ca...