Clathrin-coated vesicles (CCVs) facilitate the transport of cargo between the trans-Golgi network, endosomes, and the plasma membrane. This study presents the first comparative proteomics investigation of CCVs. A CCV-enriched fraction was isolated from HeLa cells and a "mock CCV" fraction from clathrin-depleted cells. We used a combination of 2D difference gel electrophoresis and isobaric tags ...

Papillary thyroid carcinoma (PTC), which is characterized by low incidence of distant metastases, is a common subtype of thyroid carcinoma. Metastases of the clear cell variant (CCV), one of the many PTC variants, are rare. A 73-year-old woman with a 2-year history of a growing subcutaneous tumor in the right temporal region of her skull was admitted to our hospital; the tumor was initially spe...

Columnar cell variant of papillary thyroid carcinoma (CCV-PTC) is a rare and aggressive tumor composed of tumor cells that form papillae, glands and solid structures. Fine needle aspiration on a young female patient who presented with a solitary thyroid nodule. Cytology revealed cellular smears with three dimensional clusters and papillary fragments composed of tall columnar cells. These column...

Measurements of cloud condensation nuclei (CCN), aerosol size distributions, and submicron aerosol composition were made as part of the Intercontinental Chemical Transport Experiment Phase B (INTEX-B) campaign during spring 2006. Measurements were conducted from an aircraft platform over the northeastern Pacific and western North America with a focus on how the transport and evolution of Asian ...

BACKGROUND/AIMS The CHADS2 score, used to predict the risk of ischemic stroke in atrial fibrillation (AF) patients, has been reported recently to predict ischemic stroke in patients with coronary heart disease, regardless of the presence of AF. However, little data are available regarding the relationship between the CHADS2 score and cardiovascular outcomes. METHODS This was a retrospective s...

Este estudo experimental objetivou a caracterização fonético-acústica de encontros consonantais em sílabas CCV. Participaram do crianças entre 5 e 6 anos com fala típica desvio fonológico. Os resultados mostraram que os dois grupos estão processo refinamento articulatório dos gestos envolvidos na produção das CCV, apresentando mesmos eventos acústicos caracterizam tal refinamento, como desvozea...

We have cloned, sequenced and expressed the spike (S) gene of canine coronavirus (CCV; strain K378). Its deduced amino acid sequence has revealed features in common with other coronavirus S proteins: a stretch of hydrophobic amino acids at the amino terminus (the putative signal sequence), another hydrophobic region at the carboxy terminus (the membrane anchor), heptad repeats preceding the anc...

OBJECTIVE Elevated serum gamma-glutamyl transferase (GGT) level has been proposed as a risk factor for coronary artery disease and is associated with poor clinical outcome in acute coronary syndrome (ACS). We aimed to evaluate the relationship between GGT level and presence of coronary collateral vessels (CCV) patients with ACS. METHODS We evaluated 178 patients with ACS in this cross-section...

Catfish reovirus (CRV), a double stranded RNA virus, inhibited channel catfish herpes-virus (CCV) replication by 2 different mechanisms: (1) directly as a consequence of its own replication, and (2) indirectly due to the induction of an anti-viral factor. In the former, prior infection with CRV significantly reduced subsequent CCV protein synthesis and virus yield. CRV mediated-interference was...