The F3 histones of duck erythrocytes and calf thymus have been purified and compared by a variety of techniques. The results of analytical gel electrophoresis, gel filtration, cysteine content determinations, and amino acid analysis support the conclusion that there exist two chemically and metabolically distinct forms of F3 histone. The duck erythrocyte has a single form of F3 histone, which c...

F3 and TAG-1 are two closely related adhesion glycoproteins of the Ig superfamily that are both expressed by the axons of cerebellar granule cells. In an in vitro system in which cerebellar granule cells were cultured on monolayers of transfected Chinese hamster ovary (CHO) cells, we show that F3 and TAG-1 interact functionally. F3 transfectants have been shown to inhibit outgrowth and induce f...

This paper reports on two listening experiments which explore the relative contributions of F2 and F3 in the perception of rhoticity. Experiment 1 tests the hypothesis that a low-frequency F3 is a crucial spectral component for a signal to be perceived as rhotic. Its results suggest that the removal of F3 may in fact strengthen the rhoticity percept. Experiment 2 manipulates the relative amplit...

abstract  in order to study f3´5´h and f3´h function and their intraction in the grapevine flavonoids biosynthetic pathway, designing and constraction of suitable constructs encoding ihprna was performed and transgenic lines containing silencing construct of f3´h and simultaneous silencing construct of f3´5´h and f3´h were created. for this purpose, fragments were selected from both genes and i...

The surface overexpression of nucleolin provides an anchor for the specific attachment of biomolecules to cancer and angiogenic endothelial cells. The peptide F3 is a high-affinity ligand of the nucleolin receptor (NR) that has been investigated as a carrier to deliver biologically active molecules to tumors for both therapeutic and imaging applications. A site-specific PEGylated F3 derivative ...

INTRODUCTION The F3 peptide (KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK), a fragment of the human high mobility group protein 2, binds nucleolin. Nucleolin is expressed in the nuclei of normal cells but is also expressed on the membrane of some cancer cells. The goal was to investigate the use of 111In-labeled F3 peptide for Auger electron-targeted radiotherapy. METHODS F3 was labeled with fluorescein i...