Gender Identity Disorder (GID) is characterized by a strong and persistent cross-gender identification that affects different aspects of behavior. Brain-derived neurotrophic factor (BDNF) plays a critical role in neurodevelopment and neuroplasticity. Altered BDNF-signaling is thought to contribute to the pathogenesis of psychiatric disordersand is related to traumatic life events. To examine se...

A person with a Gender Identity Disorder (GID) is a person who strongly identifies with the other sex. The individual may identify with the opposite sex to the point of believing that he/she is, in fact, a member of the other sex who is trapped in the wrong body. The treatment option is sex reassignment surgery. In Pakistan There is no specialized facility sex reassignment surgery. This case re...

In female-to-male/gender identity disorder (FTM/GID) patients, no voice therapy (VT) is required, as the administration of male hormones will naturally cause to become low-pitched. However, in male-to-female (MTF)/GID female does not high-pitched. Since 2014, we have performed type 4 thyroplasty (TP4) and preoperative postoperative VT for MTF/GID patients. this study, examined outcomes VT. The ...

Haemophilus parasuis is classified mainly through serotyping, but traditional serotyping always yields non-typable (NT) strains and unreliable results via cross-reactions. Here, we surveyed the serotype prevalence of Chinese H. parasuis isolates using traditional serotyping (gel immuno-diffusion test, GID) and molecular serotyping (multiplex PCR, mPCR). We also investigated why discrepant resul...

Graft-induced dyskinesia (GID) is a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. We have recently shown that DA D2 receptor blockade produces sticking blockade of dyskinesia induced by amphetamine in grafted 6OHDA-lesioned rats, a model of GID. This study was designed to investigate whether blockade of DA D1 receptors could produce similar outcome...

Intrusion detection system (IDS) is an important part of enterprise security system architecture. In particular, anomaly-based IDS has been widely applied to detect abnormal process behaviors that deviate from the majority. However, such abnormal behavior usually consists of a series of lowlevel heterogeneous events. The gap between the low-level events and the high-level abnormal behaviors mak...

MRCTLH (muskelin/RanBPM/CTLH) is a protein complex found in humans (MRCTLH) that involved the regulation of numerous cellular processes, such as gluconeogenesis, cell signaling, development, nuclear extrusion, morphology, or stability different proteins. According to genomic data, all eukaryotes have similar complexes. In yeast, named GID was be gluconeogenesis. LICC1 maize whose sequence resem...

Promoter-specific transcriptional activators (activators) stimulate transcription through direct interactions with one or more components of the transcription machinery, termed the "target." The identification of direct in vivo targets of activators has been a major challenge. Previous studies have provided evidence that the Tra1 subunit of the yeast SAGA (Spt-Ada-Gcn5-acetyltransferase) comple...

L-DOPA, the most effective drug to treat motor symptoms of Parkinson's disease, causes abnormal involuntary movements, limiting its use in advanced stages of the disease. An increasing body of evidence points to the serotonin system as a key player in the appearance of L-DOPA-induced dyskinesia (LID). In fact, exogenously administered L-DOPA can be taken up by serotonin neurons, converted to do...

Gender Identity Disorder (GID) is a complex problem. This report describes three cases of GID with more or less similar clinical presentation. It was interesting to note that inspite of the similarity in their early clinical features, their own approach towards their illness, the reaction of the family members and the outcome were different. The report also highlights the need for different the...