The major excreted protein (MEP) of transformed mouse fibroblasts is a mannose 6-phosphate-containing glycoprotein whose synthesis and secretion are increased in malignantly transformed 3T3 cells and whose synthesis is increased by treatment of 3T3 cells with tumor promoters or growth factors. When pulse-labeled extracts from Kirsten virus-transformed NIH 3T3 (KNIH) cells were immunoprecipitate...

The presence of two major egg polypeptides was demonstrated in the plant-parasitic nematode Heterodera glycines. The polypeptides were present in equal amounts in, and were most abundant in, eggs from yellow females. They were also present in brown females but were not detected in second-stage juveniles (J2). The two major egg polypeptides, MEP-I and MEP-II, accounted for more than 50% of the t...

The full-length cDNA sequence for metalloprotease (MEP) of Arthroderma gypseum (one of the teleomorphs of the Microsporum gypseum complex) was determined by the 5'-rapid amplification of cDNA ends (RACE) and 3'-RACE methods using cDNA as a template. The full-length cDNA sequence of the MEP (2,670 bp) gene was proved to encode 677 amino acids. The amino acid sequence of the A. gypseum MEP gene s...

The master equality polyhedron (MEP) is a canonical set that generalizes the Master Cyclic Group Polyhedron (MCGP) of Gomory. We recently characterized a nontrivial polar for the MEP, i.e., a polyhedron T such that an inequality defines a nontrivial facet of the MEP if and only if its coefficient vector forms a vertex of T . In this paper we study the MEP when it is defined by m > 1 rows. We de...

OBJECTIVE To investigate whether motor evoked potential (MEP) amplitude ratio measurements are sufficiently objective to assess functional activities of the extremities. We also delineated the distribution between the presence or absence of MEPs and the Medical Research Council (MRC) scale for muscle strength of the extremities. METHODS We enrolled 183 patients with first-ever unilateral hemi...

We have studied the effect of repeated doses of thiopentone on motor evoked potentials (MEP) after transcranial magnetic stimulation in 13 patients. Thiopentone was administered i.v. in an initial dose of 2 mg kg-1, followed by repeated doses (1 mg kg-1 every 3 min) until the appearance of burst suppression on the EEG. The total dose administered was mean 10.7 (SD 2.6) mg kg-1. The magnetic coi...

A probabilistic information retrieval method using the Maxfrom Kantor, 1994), or (b) useful for information retrieval, imum Entropy Principle (MEP) was proposed by Cooper even if it is not true. In the present article, we examine these and Huizinga (1982). Several refinements of the MEP for questions using the TREC5 (Harman, 1996, in press) biinformation retrieval have been proposed by Kantor a...

Medicinal tea tree (Melaleuca alternifolia) leaves contain large amounts of an essential oil, dominated by monoterpenes. Several enzymes of the chloroplastic methylerythritol phosphate (MEP) pathway are hypothesised to act as bottlenecks to the production of monoterpenes. We investigated, whether transcript abundance of genes encoding for enzymes of the MEP pathway were correlated with foliar t...

The major excreted protein (MEP) of malignantly transformed mouse fibroblasts is the precursor to an acid proteinase with enzymic specificity similar to that of human cathepsin L. By cross-hybridization with a mouse MEP sequence, cDNA clones of the human form of MEP in an SV40 expression vector were isolated. A 1.6 kb cDNA showed 70% deduced amino acid sequence identity with mouse MEP. The dedu...