The Asp of the RGD motif of the ligand coordinates with the β I domain metal ion dependent adhesion site (MIDAS) divalent cation, emphasizing the importance of the MIDAS in ligand binding. There appears to be two distinct groups of integrins that differ in their ligand binding affinity and adhesion ability. These differences may be due to a specific residue associated with the MIDAS, particular...

This paper describes work carried out in the ESPRIT "MIDAS" project to provide for secure management in the context of the ISO standards for network and system management. The intention of the MIDAS work is to make use of security mechanisms which have already been standardised (for example X.509 authentication) and to make these available through a conventional implementation of the CMIP proto...

The MIDAS (Multi-Instrument Data Analysis System) algorithm performs a 4dimensional mathematical inversion. It is designed to assimilate a number of different measurement techniques, thus allowing the spatial and temporal factors to be accounted for in the inversion. In this study ionospheric data have been collected together from a number of observations in Europe. The MIDAS program incorporat...

We present Midas, an economical FPGA-based architecture simulator that allows rapid early design-space exploration of manycore systems. Midas models target-system timing and functionality separately, and it employs hostmultithreading for an efficient FPGA implementation. It is a high-throughput, cycle-accurate full-system simulator, capable of booting real operating systems. The Midas prototype...

A MIDAS regression involves a dependent variable observed at a low frequency and independent variables observed at a higher frequency. This paper relates a true high frequency data generating process, where also the dependent variable is observed (hypothetically) at the high frequency, with a MIDAS regression. It is shown that a correctly specified MIDAS regression usually includes lagged depen...

This paper compares the mixed-data sampling (MIDAS) and mixed-frequency VAR (MFVAR) approaches to model speci…cation in the presence of mixed-frequency data, e.g., monthly and quarterly series. MIDAS leads to parsimonious models based on exponential lag polynomials for the coe¢ cients, whereas MF-VAR does not restrict the dynamics and therefore can su¤er from the curse of dimensionality. But if...

The polychromatic and trophically polymorphic Midas cichlid fish species complex (Amphilophus cf. citrinellus) is an excellent model system for studying the mechanisms of speciation and patterns of phenotypic diversification in allopatry and in sympatry. Here, we first review research to date on the species complex and the geological history of its habitat. We analyse body shape variation from ...

In this paper, we present Molecular Isotopic Distribution Analysis (MIDAs), a new software tool designed to compute molecular isotopic distributions with adjustable accuracies. MIDAs offers two algorithms, one polynomial-based and one Fourier-transform-based, both of which compute molecular isotopic distributions accurately and efficiently. The polynomial-based algorithm contains few novel aspe...

Automatic estimation of velocities from GPS coordinate time series is becoming required to cope with the exponentially increasing flood of available data, but problems detectable to the human eye are often overlooked. This motivates us to find an automatic and accurate estimator of trend that is resistant to common problems such as step discontinuities, outliers, seasonality, skewness, and hete...

12 benthic-limnetic axis and most populations are also color-polymorphic. The most comprehensive project focuses on the gold/dark color polymorphism in the Midas cichlid species complex (Amphilophus citrinellus spp.). Using a comparative approach that bases on extensive field collections of Midas cichlids, a substantial degree of ecological differentiation between color morphs is revealed. The ...