Algorithm to Find All Cliques in a Graph A. Ashok Kumar Department of Computer Science , St. Xavier’s College (Autonomous), Palayamkottai 627 002. E-mail: [email protected] S. Athisayanathan Research Department of Mathematics, St. Xavier’s College (Autonomous),Palayamkottai 627 002. E-mail: [email protected] A. Antonysamy Research Department of Mathematics, St. Xavier’s College...

BACKGROUND/AIMS Nonsteroidal anti-inflammatory drugs relieve osteoarthritis (OA) symptoms but cause adverse effects. D-002, a mixture of beeswax alcohols, is effective against experimental OA. A pilot study found that D-002 (50 mg/day) for 8 weeks improves OA symptoms. The aim of this study was to investigate the effects of D-002 (50 to 100 mg/day) administered for 6 weeks on OA symptoms. MET...

V.T. Nguyen College of Natural Sciences, Vietnam National University, Hanoi, Vietnam B.D. Nguyen · H.T. Nguyen Molecular Genetics and Plant Genomics Laboratory, Texas Tech University, Lubbock, TX 79409, USA S. Sarkarung International Rice Research Institute (IRRI), MCPO Box 3127, Mataki City, Philippines C. Martinez International Center for Tropical Agriculture (CIAT), Apartado Aereo 6713, Cali...

Here we studied ability of two naphthoquinones to inhibit Leishmania growth (2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone (TR 001) and 2,3-dibromo-1,4-naphthoquinone (TR 002). TR 001 was more efficient than TR 002 in inducing killing of promastigotes and intracellular amastigotes. These values compare well to those obtained with the standard first-line antileishmanial agent sodium stiboglucona...

NOV-002 is a novel glutathione disulfide mimetic that when administered in combination with standard chemotherapeutic regimens has resulted in increased efficacy (survival, tumor response) and improved tolerance to chemotherapy (e.g., hematologic recovery) in advanced non–small cell lung cancer patients. We show that NOV-002, which is not cytotoxic as a single agent, generated timeand concentra...

NOV-002 is a novel glutathione disulfide mimetic that when administered in combination with standard chemotherapeutic regimens has resulted in increased efficacy (survival, tumor response) and improved tolerance to chemotherapy (e.g., hematologic recovery) in advanced non-small cell lung cancer patients. We show that NOV-002, which is not cytotoxic as a single agent, generated time- and concent...

BACKGROUND: The treatment of Osteoarthritis (OA) is addressed to pain alleviation and functional status improvement. Non-steroidal anti-inflammatory drug (NSAIDs), widely prescribed for OA, have been show to produce gastrointestinal (non selective) and cardiovascular (ciclooxygenase– 2 inhibitors) adverse effects. Then, the search for new substances is justified. D-002 is a mixture of higher al...

Natural killer (NK) cell responses in primates are regulated in part through interactions between two highly polymorphic molecules, the killer-cell immunoglobulin-like receptors (KIRs) on NK cells and their major histocompatibility complex (MHC) class I ligands on target cells. We previously reported that the binding of a common MHC class I molecule in the rhesus macaque, Mamu-A1*002, to the in...

Introduction: policosanol, a mixture of higher aliphatic alcohols purified from sugar cane wax, is used to treat hypercholesterolemia. D-002 (Abexol), a mixture of higher aliphatic alcohols from beeswax, is an antioxidant supplement with gastroprotective effects. Then, concomitant intake of D-002 and policosanol may occur in routine practice, so potential pharmacological interactions between th...

Nonsteroidal antiinflammatory drugs include the traditional drugs and more selective COX-2 inhibitors. Traditional nonsteroidal antiinflammatory drug use is hampered by their gastrotoxicity, while COX-2-inhibitors increase the cardiovascular risk. The search of safer substances for managing inflammatory conditions is updated, a challenge wherein dual COX/5-LOX inhibitors have a place. This revi...