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An obstacle to stem cell gene therapy for AIDS is the limited numbers of hematopoietic progenitors available. Granulocyte colony-stimulating factor (G-CSF) is used for mobilization of progenitors, but little is known about the functional characteristics of mobilized progenitors, and immature and T cell progenitors may not be mobilized. This study examined the effect of G-CSF on the function of ...
Neurokinin A (NKA) causes bronchoconstriction in asthmatic patients. In vitro both NK1 and NK2 receptors can mediate airway contraction. Moreover in guinea pigs, NK3 receptors facilitate cholinergic neurotransmission. Dual tachykinin NK1/NK2 receptor antagonism results in prevention of NKA-induced bronchoconstriction. We have now examined the effect of a single dose of the triple tachykinin rec...
Abstract A 2 mm gas gap Resistive Plate Chamber with bakelite plates has been operated in avalanche mode under a 137Cs source irradiation. We report on measurements of the efficiency in cosmic rays detection and of the charge developed in the gap, performed for two different gas mixtures: the first containing a high percentage of environmental friendly ”freon” C2H2F4; the second one having a hi...
Introduction The PFAPA syndrome is a non-mendelian autoinflammatory disease of unknown aetiology characterized by Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis. In typical cases, attacks begin before the age of five and occur every 2-8 weeks, often with striking periodicity. We have previously profiled the blood cells and serum cytokine levels in a cohort study of pati...
Back cover image: The crystal plane exposure is of great significance to the structural stability layered cathodes. In article number 10.1002/cey2.298, Qiu and co-workers deciphered degradation discrepancy Ni-rich cathode with a diverse proportion [003] crystallographic textures, revealing structure-activity relationship between face oxygen release stability. Although textures was conducive Li+...
2:30 p.m. 2:45 p.m. OF MICE, MEN AND PIGS: LOSS OF CFTR PRODUCES ABNORMAL TRACHEAL DEVELOPMENT D.K. Meyerholz, S. Ramachandran, D.A. Stoltz, M.J. Welsh, and P.B. McCray, Jr. Departments of Pathology, Pediatrics, Internal Medicine, Molecular Physiology and Biophysics, and Howard Hughes Medical Institute, Roy Carver College of Medicine, University of Iowa, Iowa City, IA Keyword: Respiratory Syste...
Increasing evidence implicates long noncoding RNAs (lncRNAs), a class of noncoding RNAs >200 nucleotides in length, in the development of cancer. However, the mechanism underlying the effects of lncRNAs in prostate cancer (PCa) remains to be elucidated. The present study aimed to investigate the role of lncRNA‑THBS4‑003 in the pathogensis of PCa. In the present study, a microarray containing 8,...
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