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Marrow cells from 36 patients with myelodysplastic syndromes (MDS) (13 refractory anemia [RA], 14 refractory anemia with excess of blasts [RAEB], 9 RAEB in transformation [RAEB-T]) were evaluated for their in vitro proliferative and differentiative responsiveness to recombinant human granulocyte colony-stimulating factor (G-CSF) or granulocyte-monocyte CSF (GM-CSF). GM-CSF exerted a stronger pr...
Reviewer: 1 Comments to the Author This paper have technical weak points.First the background and references are not adequate!The locality characteristics are found not only with characteristics of 2-tier architecture but also with 3-tier etc. Thus locality characteristics are examined not only in a temporal context but also in client temporal context particularly for web based streams... Secon...
Inhibition of mitochondrial permeability transition pore (mPTP) opening by cyclosporin A or ischemic postconditioning attenuates lethal reperfusion injury. Its impact on major post-myocardial infarction events, including worsening of left ventricular (LV) function and death, remains unknown. We sought to determine whether pharmacological or postconditioning-induced inhibition of mPTP opening mi...
CONTEXT Sex differences in lower extremity landing mechanics and muscle activation have been identified as potential causative factors leading to the increased incidence of anterior cruciate ligament injuries in female athletes. Valgus knee alignment places greater strain on the anterior cruciate ligament than a more neutral alignment. Gluteus medius (GM) activation may stabilize the leg and pe...
Adults ( N = 54, 80.78 ± 6.08 years) who reported falling during the previous 12 months participated in a 12-week wobble board training program with internal focus or external (EF) instructions. Verbal manipulation checks were performed after sessions as self-report of attentional foci used. The percentage which participants using an EF (EF SR ) was subsequently calculated. Mean velocity and me...
E Demirkaya, C Acikel, A Tufan, A Kucuk, A Berdeli, A Gul, AM Onat, A Delibas, A Duzova, A Dinc, O Yavascan, O Kasapcopur, B Makay, B Goker, B Sozeri, B Kisacik, E Comak, E Unsal, E Erken, E Gunal, E Baskin, F Yalcinkaya, F Yildiz, F Gok, G Basbozkurt, G Ozcelik, G Demircin, H Poyrazoglu, H Erdem, H Direskeneli, H Ozer, H Ozdogan, I Simsek, I Dursun, I Gokce, M Tunca, M Gurgoze, N Cakar, N Akin...
Introduction Cryopyrin-associated periodic syndrome (CAPS), clinically characterized by neutrophil-rich urticarial rash, is associated with missense mutations in NLRP3. NLRP3 is a pattern recognition receptor in the cytoplasm of cells and structurally related to plant resistance proteins, which detect pathogenor danger-associated signals, leading to programmed cell death and hyper response at t...
The purine metabolic enzymes adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) are important in lymphocyte differentiation, and genetic deficiencies of either enzyme have been associated with hereditary immunodeficiency states. Both ADA and PNP activity were measured in null cell-enriched and T cell-enriched peripheral blood lymphocytes from 16 patients with the acquired immun...
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