Effects of OKY-046, a selective inhibitor of thromboxane (TX)A2 synthetase and a platelet aggregation inhibitor, on in vitro and in vivo models of cerebral vasospasm were studied. The contraction of the isolated rabbit basilar artery by an exposure to 1.0 ml of whole rabbit blood plus 0.05 or 0.1 units/ml of thrombin was diminished by the treatment with 10(-4) M of OKY-046 and/or 10(-6) M of ci...

We present results and first epoch parsec-scale images from a monitoring program on five γ–ray loud blazars selected on the basis of their total flux density variability. We observed 0048−097, 0235+164, 0954+658, 1510−089 and 1749+096 with the Very Long Baseline Array simultaneously at 8.4 GHz and 22 GHz. Comparison between our high quality images and previous results from the literature sugges...

We examine the power of Boolean functions with low L 1 norms in several settings. In large part of the recent literature, the degree of a polynomial which represents a Boolean function in some way was chosen to be the measure of the complexity of the Boolean function (see, e. have high degree, but small L 1 norms. So, in conjunction with communication complexity, instead of the degree, the L 1 ...

In vortex particle methods one is concerned with the problem of clustering and depletion of particles in different regions of the flow. The overlap of the vortex blobs is indeed of primary importance for the convergence of the method. In this paper we consider face-centred cubic (FCC) lattices for particle redistribution in three dimensions. This lattice is in fact the most natural way to pack ...

We encountered an unfamiliar ascomycete fruiting body, fitting characteristics of the genus Kretzschmaria, which features in a stipitate ascigerous stroma with carbonaceous interior and disintegrating perithecia. In this study, we report and characterize a new species of the decaying fungus. Compared to other species, one of the notable features of this specimen (TPML150908-046) is its stromata...

Polarization offers a unique view in the physical processes of astrophysical jets. We report on optical circular polarization observations two famous blazars, namely 3C 279 and PKS 1510-089, at high linearly polarized states. This is first time 1510-089 observed polarization. While only upper limits can be extracted from our observing campaign, non-detection allows us to provide meaningful cons...

The effect of a selective thromboxane (TX) synthetase inhibitor (OKY-046), alone and in combination with a very low dose of aspirin, on the platelet function was studied in healthy and diseased subjects. A single dose of 100 mg OKY-046 was orally administered to patients with ischemic cerebrovascular disease (CVD) and healthy volunteers. TXB2 generation and platelet aggregation were measured be...

On the occasion of the thirty-first anniversary of the publication of The Multinational Corporation and the Law of Uneven Development by Hymer, the paper seeks to assess the relevance of Hymer’s prediction to our current understanding of the multinational company (MNC) and its role in world economic development. It argues that the largely ethnocentric type of MNC portrayed by Hymer is descripti...