We have searched for molecular absorption lines at millimeter wavelengths in eleven gravitational lens systems discovered in the JVAS/CLASS surveys of flat spectrum radio sources. Spectra of only one source 1030+074 were obtained in the 3-, 2and 1.3-millimeter band at the frequencies corresponding to common molecular transitions of CO and HCO as continuum emission was not found in any of the ot...

Recent studies have linked necrotic cell death and proteolysis of inflammatory proteins to the adaptive immune response mediated by the lysosome-destabilizing adjuvants, alum and Leu-Leu-OMe (LLOMe). However, the mechanism by which lysosome-destabilizing agents trigger necrosis and proteolysis of inflammatory proteins is poorly understood. The proteasome is a cellular complex that has been show...

The roles of cellular proteases in Moloney murine leukemia virus (MLV) infection were investigated using MLV particles pseudotyped with vesicular stomatitis virus (VSV) G glycoprotein as a control for effects on core MLV particles versus effects specific to Moloney MLV envelope protein (Env). The broad-spectrum inhibitors cathepsin inhibitor III and E-64d gave comparable dose-dependent inhibiti...

The invasion and replication of Eimeria tenella in the chicken intestine is responsible for avian coccidiosis, a disease that has major economic impacts on poultry industries worldwide. E. tenella is transmitted to naïve animals via shed unsporulated oocysts that need contact with air and humidity to form the infectious sporulated oocysts, which contain the first invasive form of the parasite, ...

1 Laboratoire Pierre Aigrain, Ecole Normale Supérieure, 24 rue Lhomond, 75231 Paris Cedex 5, France 2 CNRS UMR8551, Université Pierre et Marie Curie, 24 rue Lhomond, 75005 Paris, France 3 Laboratoire de Physico-Chimie des Matériaux Luminescents, Université Lyon 1, Université de Lyon, Campus de la Doua, 69622 Villeurbanne, France 4 Université Montpellier 2, CC 074, 34095 Montpellier Cedex 5, France