Background Double-blind, placebo-controlled food challenge (DBPCFC) is considered the gold standard for food allergy diagnosis. However, this test is rarely performed routinely in clinical practice because of various practical issues, e.g. the lack of a standardized matrix preparation. The aim of this study was to develop and validate a convenient DBPCFC matrix, that can easily be implemented i...

We have studied the contribution of platelets to the coagulation of plasma and the effects of activation or inhibition of platelets on the coagulation process in unanticoagulated fresh whole blood (subsequently termed native blood). For this purpose, we have used a free oscillation rheometer (FOR), the ReoRox4, a new instrument that enables noninvasive viscoelastic measurements of clot formatio...

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTShaping Effective Practices for Incorporating Sustainability Assessment in Manuscripts Submitted to ACS Sustainable Chemistry & Engineering: Catalysis and Catalytic ProcessesDamien P. DebeckerDamien DebeckerMore by Damien Debeckerhttp://orcid.org/0000-0001-6500-2996, King Kuok (Mimi) HiiKing HiiMore Hiihttp://orcid.org/0000-0002-1163-0505, Audrey Moores...

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTEthanol from Sugarcane and the Brazilian Biomass-Based Energy Chemicals SectorLiane M. RossiLiane RossiMore by Liane Rossihttp://orcid.org/0000-0001-7679-0852, Jean Marcel R. GalloJean GalloMore Gallohttp://orcid.org/0000-0003-2937-2628, Luiz H. C. MattosoLuiz MattosoMore Mattosohttp://orcid.org/0000-0001-7586-1014, Marcos S. BuckeridgeMarcos Buckeridge...

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTCan CO2 and Renewable Carbon Be Primary Resources for Sustainable Fuels Chemicals?M. M. Faruque HasanM. HasanMore by Hasanhttps://orcid.org/0000-0001-9338-6069, Liane RossiLiane RossiMore Rossihttps://orcid.org/0000-0001-7679-0852, Damien P. DebeckerDamien DebeckerMore Debeckerhttps://orcid.org/0000-0001-6500-2996, Kevin C. LeonardKevin LeonardMore Leon...

A critical function of fibrinogen in hemostasis and thrombosis is to mediate platelet aggregation by binding selectively to an activated form of glycoprotein (GP) IIb/IIIa. Although numerous peptide and nonpeptide fibrinogen receptor antagonists have been described, their binding selectivity for resting and activated platelets has not been explored. Therefore, dissociation constants of GP IIb/I...

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTBuilding Pathways to a Sustainable PlanetDavid T. AllenDavid AllenMore by David Allenhttps://orcid.org/0000-0001-6646-8755, Peter LicencePeter LicenceMore Licencehttps://orcid.org/0000-0003-2992-0153, Bala SubramaniamBala SubramaniamMore Subramaniamhttps://orcid.org/0000-0001-5361-1954, Paul AnastasPaul AnastasMore Anastashttps://orcid.org/0000-0003-477...

TOPIC: Pulmonary Manifestations of Systemic Disease TYPE: Medical Student/Resident Case Reports INTRODUCTION: Antiphospholipid Syndrome (APS) is an autoimmune disorder clinically defined by the presence antiphospholipid antibodies (aPL), history arterial or deep venous thrombosis (DVT), and/or repeat episodes early pregnancy loss. Due to increased risk for thrombosis, often overlooked a rare an...

TOPIC: Pulmonary Vascular Disease TYPE: Medical Student/Resident Case Reports INTRODUCTION: We present a case of middle-aged female with antiphospholipid syndrome (APS) presenting as atypical pneumonia and alveolar hemorrhage later confirmed to have APS-induced vasculitis. CASE PRESENTATION: 65 years APS positive anti-cardiolipin beta2 glycoprotein antibodies presented the Emergency Department ...