Estrogens have an important role in regulating detrusor smooth muscle (DSM) function. However, the underlying molecular and cellular mechanisms by which estrogens control human DSM excitability and contractility are not well known. Here, we used human DSM specimens from open bladder surgeries on 27 patients to elucidate the mechanism by which 17β-estradiol regulates large conductance voltage- a...

An experimental study was conducted to investigate developmental changes of the rat detrusor smooth muscle (DSM) reactivity from newborn to adult period. Urinary bladders were obtained from adult (4 months old), 1-month-old and newborn (4-7 days old) male Sprague-Dawley rats. DSM reactivity of the three groups was evaluated in organ chambers. The newborn DSM strips revealed markedly increased p...

T he Diagnostic and Statistical Manual of Mental Disorders (DSM) is the most important resource for the purpose of psychiatric diagnoses, whether by the psychiatrist or the general practitioner. The American Psychiatric Association published the fifth edition of DSM (DSM-5) [1], containing significant changes in the diagnostic criteria for certain disorders from those in DSM-IV, which had been ...

We propose an optimized Structure-from-Motion (SfM) Multi-View Stereopsis (MVS) workflow, based on minimizing different errors and inaccuracies of historical aerial photograph series (1945, 1979, 1984, 2008 surveys), prior to generation elevation-calibrated Digital Surface Models (hDSM) at 1 m resolution. applied LiDAR techniques Airborne Laser Scanning (ALS) point clouds (Spanish PNOA flights ...

An experiment was carried out using pots in the plastic house of Agricultural Research Station / College Agriculture University Basrah Karma Ali site during year 2022, to study effect adding mineral sulfur, organic matter, leaching requirements, and salinity irrigation water on soil planted with maize plants. By two types residuses (cow alfalfa residuses) three levels added sulfur (0%, 0.8% 1.6...

OBJECTIVE This study aimed (1) to describe frequencies of DSM IV somatisation disorder, undifferentiated somatoform disorder and pain disorder versus DSM 5 somatic symptom disorder (SSD) in a multi-setting population of patients with medically unexplained physical symptoms (MUPS), (2) to investigate differences in sociodemographic and (psycho)pathological characteristics between these diagnosti...

The Diagnostic and Statistical Manual on Mental Disorders (DSM) represents the current thinking on the symptomology of mental illness, from the perspective of the American Psychiatric Association. The most recent version, DSM-5, was published in May 2013 after nearly two decades of research and a highly politicized revision process.1 Intended primarily as an aid in the diagnosis and treatment o...

The fifth version of the Diagnostic and statistical manual of mental disorders (DSM-5) was released in May 2013 after 14 years of development and almost two decades after the last edition DSM-IV was published in 1994. We review the DSM journey with regards to Tourette Syndrome from the original publication of DSM 1 in 1952 till date. In terms of changes in DSM 5, the major shift has come in the...