The aim of this work was to demonstrate the occurrence of oxidative stress during exhaustive exercise and to determine the antioxidant response. Eight voluntary male subjects participated in this study. The exercise was a cycling mountain stage (171 km) and the cyclists took a mean+/-S.E.M. time of 270+/-12 min to complete it. Blood samples were taken before the cycling stage, immediately after...

OBJECTIVE To test the hypothesis that salidroside (SAL) can protect heart from exhaustive exercise-induced injury by enhancing mitochondrial respiratory function and mitochondrial biogenesis key signaling pathway PGC-1α-NRF1/NRF2 in rats. METHODS Male Sprague-Dawley rats were divided into 4 groups: sedentary (C), exhaustive exercise (EE), low-dose SAL (LS), and high-dose SAL (HS). After one-t...

BACKGROUND The protective effect of Erythropoietin (EPO) analogue rHuEPO on acute renal injury induced by exhaustive exercise had been reported. The purpose of this study is to probe into the protective effect of EPO on chronic renal injury induced by repeated exhaustive exercise for four weeks. METHODS Eighty adult male Sprague-Dawley rats were used in this experiment. The animals were rando...

l-Arginine (l-Arg) supplementation has been shown to enhance physical exercise capacity and delay onset of fatigue. This work investigated the potential beneficial mechanism(s) of l-Arg supplementation by examining its effect on the cellular oxidative and nitrosative stress pathways in the exercised rats. Forty-eight rats were randomly divided into six groups: sedentary control; sedentary contr...

this study was conducted to compare of inflammatory markers response in serum and saliva of healthy men following an exhaustive exercise test. twenty two volunteer healthy men (aged 20-30 years and body fat 10-16%) in a quasi-experimental, single group design participated in bruce exercise test. serum and saliva samples were collected immediately before and after the exercise test. c-reactive p...

conclusions the findings suggest that estrogen supplementation increases damage in testicular tissue due to eccentric exercise. results conventional light microscopic results revealed that testes tissues of the eccentric exercise administered group and the estrogen supplemented group exhibited slight impairment. in groups that were both eccentrically exercised and estrogen supplemented, more de...