نتایج جستجو برای: 1 selective alzheimer disease indicator
تعداد نتایج: 4080814 فیلتر نتایج به سال:
donepezil, a member of the acetylcholinesterase inhibitor family, is approved for management of cognitive impairments as well as behavioral complications in patients with neurodegenerative alzheimer's disease. generally, donepezil is regarded as a safe medication in patients with alzheimer's disease although there have been reports of several minor adverse events including gastrointestinal dist...
background: alzheimer’s disease (ad) is a progressive neurodegenerative disease and nowadays the role of endothelial cell (ec) injury has been proposed in pathological process in ad. peroxisome proliferator‑activated receptor‑γ (ppar‑γ) agonist has anti‑inflammatory properties through activation in glial cells and improves vascular function and prevent atherosclerotic disease progression. the a...
Objectives: Alzheimer’s disease is the most common kind of dementia in the old age, and its incidence increases with age. Previous studies have shown that cytokines are proteins that play an important role in inflammation, and their level changes in inflammatory diseases. Since Alzheimer’s disease is an inflammatory disease, cytokines may influence the occurrence of t...
background: metal ions effect on homeostasis of alzheimer’s disease (ad) patients. the aim of this study was to assess the metal ions (iron, zinc and copper) and cbc in patients with ad in comparison with normal range. methods: the samples of study were 17 patients with ad in tehran’s aging centers in 2015, selected as an access sample. blood samples were analyzed in a pathobiology laboratory. ...
background: sporadic alzheimer’s disease (sad) is caused by genetic risk factors, aging and oxidative stresses. the herbal extract of rosa canina (r. canina), tanacetum vulgare (t. vulgare) and urtica dioica (u. dioica) has a beneficial role in aging, as an anti-inflammatory and anti-oxidative agent. in this study, the neuroprotective effects of this herbal extract in the rat model of sad was i...
OBJECTIVE To compare cued recall measures with other memory and nonmemory tests regarding their association with a biomarker profile indicative of Alzheimer disease (AD) in CSF among patients with mild cognitive impairment (MCI). METHODS Data were obtained by the German Dementia Competence Network. A total of 185 memory clinic patients fulfilling broad criteria for MCI (1 SD deficit in memory...
BACKGROUND Lewy bodies (LB) are present in at least 20% to 30% of persons with Alzheimer disease (AD) and contribute to the risk of psychosis and to excess cognitive burden. OBJECTIVE To determine whether altered striatal dopamine receptor binding is associated with LB and psychosis in AD. DESIGN Postmortem case control. SETTING Alzheimer's Disease Research Center at the University of Pit...
P 59: Non-Steroidal Anti-Inflammatory Drugs as a Prevention of Alzheimer Disease: Risks and Benefits
Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. The exact cause of Alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. This brings in mind using non-steroidal anti-inflammatory drugs (NSAID) as treatment or prevention of the disease. ...
introduction:brain imaging with f-18 fluorodeoxyglucose (18f-fdg) positron emission tomography or tc-99m hexamethylpropyleneamine oxime (99mtc-hmpao) spect is widely used for the evaluation of alzheimer's dementia (ad); we aim to assess superiority of one method over the other. methods: twenty four patients with clinical diagnosis of alzheimer disease underwent 18f-fdg pet and 99mtc-...
Ongoing interest in brain ischemia research has provided data showing that ischemia may be involved in the pathogenesis of Alzheimer disease. Brain ischemia in the rat produces a stereotyped pattern of selective neuronal degeneration, which mimics early Alzheimer disease pathology. The objective of this study was to further develop and characterize cardiac arrest model in rats, which provides p...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید