نتایج جستجو برای: 1065 107221 mcarthur
تعداد نتایج: 1063 فیلتر نتایج به سال:
The crystal and molecular structure of a potent antitumor agent, CC1065 (C37H33N708), has been determined, and circular dichroism studies have demonstrated a strong interaction between CC-1065 and DNA. The triclinic unit cell, space group P1, of dimensions a = 11.063 (3) A, b = 13.311 (2) A, c = 13.405 (2) A, a = 85.18 (1)O, @ = 99.52 (l)', and y = 103.36 (2)O, contains two CC-1065 molecules an...
X-linked brain malformation phenotype with microcephaly and hypoplasia of the brainstem and cerebellum Juliane Najm1,13, Denise Horn2,13, Isabella Wimplinger1, Jeffrey A Golden3, Victor V Chizhikov4, Jyotsna Sudi4, Susan L Christian4, Reinhard Ullmann5, Alma Kuechler6, Carola A Haas7, Armin Flubacher7, Lawrence R Charnas8, Gökhan Uyanik9, Ulrich Frank10, Eva Klopocki2, William B Dobyns4,11,12 &...
A new antitumor antibiotic is produced in fermentation liquors of Streptomyces zelensis sp.n. The antibiotic is biologically active at extremely low concentrations. At 40 pg/ml, it inhibited 90% of the growth of L1210 cells in culture in tube dilution assays. The minimal inhibitory concentrations against Gram-positive bacteria is between 1 approximately 10 ng/ml, while these values for Gram-neg...
A liquid chromatographic method using electrochemical detection is presented for measuring the thiol WR-1065 12-(3-aminopropylamino) ethanethiol] and its symmetrical disulfide WR-33278 [NH2(CH2)3NHCH2CH2S]2. WR- 1065 is the active, radioprotective drug derived from the phosphorothioate pro-drug WR-2721 (amifostine). External standard curves for both compounds were linear over the range of 40-20...
Abstract Angeline G Burrell, McArthur Jones Jr, Alexa Halford, Kate Zawdie and John Coxon have collaborated to create a set of tools tackle conscious unconscious bias in space physics research
David Graddol talks to three people with very different professional relationships to global English: Tom McArthur, Editor of English Today and the Oxford Companion to the English Language, David Flack, Senior Creative Director of MTV Asia, and Julian Amey, Director General of Canning House. In these three interviews, Tom McArthur takes a global view of English, David Flack assesses English in ...
To explore the radioprotective effect of a standardized North American ginseng extract (NAGE) on human peripheral blood lymphocytes (PBL), a micronuclei (MN) assay was conducted in PBL obtained from 12 volunteers. NAGE (50-1000 microg/mL) and WR-1065 (1 mM and 3 mM) were applied to PBL cultures at 0 h and 90 min post-irradiation. It was found that (1) the baseline MN yield of PBL ranged from 14...
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