Damage caused by water shortages leads to physiological and biochemical changes in metabolism of plants and make them predispose to attack by pests and diseases and reduce the quality of the crops. In order to evaluate the effect of supplemental irrigation on safflower fly (A. helianthi) population of safflower cultivars, an experiment conducted as a split plot based on randomized complete bloc...

Measuring evapotranspiration (ET) components in cotton fields under mulched drip irrigation is needed to improve water use efficiency and promote the development of water-saving agriculture. In this study, an Eddy Covariance (EC) system was used observe water-carbon fluxes arid region during two years (2021–2022). The Underlying Water Use Efficiency (uWUE) method partition ET into transpiration...

How does a virus bud from the plasma membrane of its host? Here we investigate several possible rate-limiting processes, including thermal fluctuations of the plasma membrane, hydrodynamic interactions, and diffusion of the glycoprotein spikes. We find that for bending moduli greater than 3 x 10(-13) ergs, membrane thermal fluctuations are insufficient to wrap the viral capsid, and the mechanic...

BACKGROUND Establishing a new prognostic factor for early-stage cancer may seem difficult due to the small number of disease-specific deaths. Tumor budding has been recognized as a useful microscopic finding reflecting biological activity of the tumor. METHODS Tumor budding stand for isolated single cancer cells and cell clusters scattered beyond the tumor margin at the invasive front. It was...

OBJECTIVES This study investigated prognostic significance of tumor budding in early-stage cervical cancer (ESCC) following radical surgery and its contribution to improve the stratification of patients with recurrence risk. METHODS The archival medical records and H&E-stained slides of 643 patients with IA2-IIA stage cervical cancer who underwent radical surgery were retrospectively reviewed...

Like other enveloped viruses, HIV-1 uses cellular machinery to bud from infected cells. We now show that Tsg101 protein, which functions in vacuolar protein sorting (Vps), is required for HIV-1 budding. The UEV domain of Tsg101 binds to an essential tetrapeptide (PTAP) motif within the p6 domain of the structural Gag protein and also to ubiquitin. Depletion of cellular Tsg101 by small interferi...

Harvest time and storage had significant effects on nutrient quality Volatile Organic Compounds (VOCs) of alfalfa. The objective this study was to use headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) analyze alfalfa at different harvest periods (budding stage, early blooming, full blooming), for 0 d, 90 180 270 360 the dynamic changes in VOCs nutritiona...

Introduction: CRC is commonest human carcinoma and leading causes of cancer-related death worldwide. “Tumor budding” 4 or more tumor cells in invasive front colorectal adenocarcinoma glands invading up to adjacent stroma, can act as independent prognostic marker for staging which changes prognosis further treatment plans
 Objective: Association budding with stage tumour lymph node status.&...

In budding yeast, two classes of post-Golgi secretory vesicles carrying different sets of cargoes typified by Bgl2p and invertase are delivered to the plasma membrane for secretion. The exocyst is implicated in tethering these vesicles to the daughter cell membrane for exocytosis. In this study, we report that mutations in the exocyst component Exo70p predominantly block secretion of the Bgl2p ...

Article info: Received: 27 August 2014 Accepted: 13 November 2014 ABSTRACT Root biomass accumulation in spring and winter varieties and hybrids pea was recorded in field experiment in the Institute of Forage Crops, Pleven, Bulgaria (2011-2013). Spring (Shtambovyi and Pleven 4) and winter (Rosacrono and Pleven 10) varieties and their hybrids (Shtambovyi x Pleven 10 and Rosacrono х Pleven 4) (in ...