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© SINPE-GASAPE ABSTRACT: Background: Abdominal catastrophe, suture leakage and wound dehiscence are serious complications of surgical procedures. Wound infection is a frequent complication and the mortality is high due to long and difficult treatment procedures. Treatment is often difficult as a result of fistula formation, presence of necrotic and infected tissue, and complex surgical manageme...

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1. The structure of one class of giant tangential neurons in the lobula plate of Calliphora, the `Vertical System (VS)' has been investigated by light microscopy. Different staining and reconstruction procedures were employed to ensure that all existing VS-neurons are revealed. 2. There are 11 VS-cells in a characteristic, and constant arrangement (Fig. 2). Each cell covers a particular area of...

BACKGROUND scVEGF/(177)Lu is a novel radiopharmaceutical targeted by recombinant single-chain (sc) derivative of vascular endothelial growth factor (VEGF) that binds to and is internalized by vascular endothelial growth factor receptors (VEGFR). scVEGF/(177)Lu potential as adjuvant and neoadjuvant anti-angiogenic therapy was assessed in metastatic and orthotopic mouse models of triple-negative ...

UNLABELLED One mechanism of resistance to trastuzumab in human epidermal growth factor receptor-2 (HER2)-positive breast cancer (BC) is increased epidermal growth factor receptor (EGFR) expression. We have developed (111)In-labeled bispecific radioimmunoconjugates (bsRICs) that bind HER2 and EGFR on BC cells by linking trastuzumab Fab fragments through a polyethylene glycol (PEG24) spacer to ep...