Muurola-4,10(14)-dien-3-one (1), 10-O-acetyl-15-oxo-alpha-cadinol (2), 15-hydroxy-alpha-cadinol (3), 4alpha-hydroxy-5beta-ethoxy-epi-cubenol (4), and 4alpha-hydroxy-5beta-acetoxy-epi-cubenol (5), five new bicyclic sesquiterpenes, have been isolated from the heartwood of Chamaecyparis obtusa var. formosana along with the known compounds epi-cubenol, T-cadinol, T-muurolol, delta-cadinol, and alph...

The asymmetric unit of the title compound, C(10)H(9)NO, contains two independent mol-ecules which are linked by a pair of O-H⋯N hydrogen bonds into a hydrogen-bonded dimer.

The title compound, C(20)H(12)Cl(3)N(3)O(2), was synthesized by the reaction of 2-(2-hydroxy-phen-yl)benz[e][1,3]oxazin-4-one with 2,4,6-trichloro-phenyl-hydrazine in ethanol. The trichloro-phenyl ring is nearly perpendicular to the triazole plane [dihedral angle 80.56 (8)°], whereas the two hydroxy-phenyl rings are approximately coplanar with the triazole ring [dihedral angles of 2.79 (12) and...

In the title compound, [Cu(C(7)H(5)O(3))(NO(3))(C(14)H(12)N(2))], the Cu(II) ion is five-coordinated in a slightly distorted square-pyramidal geometry by one O atom of a nitrate anion, two O atoms of a 4-hydroxy-benzoate anion, and two N atoms from a bidentate 2,9-dimethyl-1,10-phenanthroline (dmphen) ligand. In the crystal structure, inversion-related mol-ecules are linked into dimers by O-H⋯O...

Clarithromycin and its metabolite, 14-hydroxy-clarithromycin are active against a wide range of respiratory pathogens. Antibiotics generally penetrate poorly into respiratory secretions which may therefore continue to harbour bacteria following bronchial infection. We have studied sputum and serum concentrations of clarithromycin and 14-hydroxy-clarithromycin in eight patients with idiopathic b...

The bactericidal activities and postantibiotic effects (PAE) of clarithromycin-14-hydroxy-clarithromycin and amoxicillin-clavulanate against Bacteroides fragilis and Peptostreptococcus anaerobius were determined. A concentration of twice the MIC resulted in bactericidal activity against four of four and three of four organisms at 24 h with clarithromycin-14-hydroxy-clarithromycin and amoxicilli...

Laboratory of Plant Pathology, Faculty of Agri culture, Nagoya University , Anjo, Japan I. タ バ コ葉diskで のuracil-2-14Cの と りこ み 実験 方 法: タバ コ (品種Bright Yellow種) の切 取 葉 を中肋 か ら2分 し, 半 葉 にTMVを 接 種 , 半 葉 は 対 照 とした. 各 半 葉 か ら径12mmのdiskを 抜 き, そ れ ぞれ 別 の ペ ト リ 皿内 の 蒸 溜 水 上 に浮 か べ , これ を25°C の 恒温 箱 に お さめ, 螢 光 灯 で 連 続 照 明 した. 各 ペ トリ皿 内 のdisk数 は28枚 , 蒸 溜 水 の 液 量 は15mlで あ る. 接 種 して か ら一 定 時 間毎 に, 接 種 対 照 両 ...