N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone (BBNH) inhibits both the DNA polymerase and ribonuclease H (RNase H) activities of the human immunodeficiency virus type 1 reverse transcriptase. In this study, we show that BBNH binding impacts on the stability of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) heterodimer. The Gibbs free energy of dimer di...

A novel Schiff base 2, 4- Bis (2‑hydroxy naphthaldehyde) diiminotholuene (L), was prepared and characterized by the analysis techniques: FT-IR, UV-Vis,1H 13C NMR. X-Ray Diffraction (XRD), showing that L crystallized in phenol-imine form. The corrosion inhibition of carbon steel 1 M hydrochloric acid solutions ligand studied using chemical (weight loss) electrochemical (potentiodynamic impedance...

A hexadentate Schiff base tripodal ligand is synthesized by the condensation of tris (2-aminoethyl) amine with 2-hydroxy-1-naphthaldehyde and characterized by various spectroscopic techniques like UV-VIS, IR, NMR, MASS, and elemental analysis. The solution studies by potentiometric and spectrophotometric methods are done at 25 ± 1°C, µ = 0.1 M KCl, to calculate the protonation constants of the ...