Correspondence Professor Giuseppe Di Giovanni, Department of Physiology and Biochemistry, University of Malta, Msida MSD 2080, Malta and Neuroscience Division, School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK. Tel.: +356 23402776 Fax: +356 21310577 E-mails: [email protected] and [email protected] Received 24 August 2015; revision 15 October 2015...

1 Applied Microbiology and Molecular Biotechnology Research Group, Department of Molecular Biology and Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece 2 Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AD, UK 3Department of Food Studies and Environmental Health, Faculty of Health Sciences, University of Malta, Msida MSD 2080, Malta 4 Inst...

Pyrrolomycins C, D and E, new members of pyrrolomycins produced by Actinosporangium vitaminophilum SF-2080, have been isolated by chromatography on a basic alumina column. Three antibiotics have chlorinated pyrrole nuclei linked directly or via carbonyl function to the dichlorophenol moiety. Pyrrolomycins C and E are active against Gram-positive bacteria, while the spectrum of pyrrolomycin D is...