Three patients with suspected iatrogenic cerebral air embolism had cranial CTs performed within 24 hr of onset of symptoms. One was interpreted as normal, one showed a large, right frontoparietal enhancing lesion, and the third showed evidence of bi-thalamic infarction. Follow-up scans 7 to 10 days later showed either single or multiple enhancing infarcts in all patients. Although CT proved a v...

1 Centre de Référence des Maladies Héréditaires du Métabolisme, Hôpital d’Enfants, CHU Brabois, Vandoeuvre les Nancy, France 2 UBC Department of Medical Genetics, Children’s Hospital Research Institute, Vancouver, Canada 3 Azienda Ospedaliera Universitaria, Catania, Italy 4 Kaiser Permanente Medical Center, Sacramento, California, USA 5 Manchester Children’s Hospital, Manchester, UK 6 Children’...

Biomaterial-based strategies to restore connectivity after lesion at the spinal cord are focused on bridging the lesion and providing an favourable substrate and a path for axonal re-growth. Following spinal cord injury (SCI) a hostile environment for neuronal cell growth is established by the activation of multiple inhibitory mechanisms that hamper regeneration to occur. Implantable scaffolds ...

An increasing number of microRNAs (miRNAs) have been identified as diagnostic and prognostic biomarkers, as well as additional therapeutic tools, in skeletal diseases. Recent studies have established the pathophysiological role of miR‑214, using human osteoporotic bone specimens. However, miR‑214 expression levels and the underlying regulatory mechanism in human osteosarcoma remain unclear. Qua...

The paper examines the rise fall and rise of the Liberal International Economic Order over the last 150 years, and critically examines the various hopes and fears in developed and developing countries that this most recent global integration is raising. JEL classification: F02, A13, N70, P16. Address: Dept. of Economics, UCLA, 405 Hilgard Ave., Los Angeles, CA 90024 Tel.: 310-825 4521 Fax.: 310...

Therapeutic hypothermia (TH) may induce pharmacokinetic changes that may affect the level of sedation. We have compared the disposition of morphine, midazolam, fentanyl, and propofol in TH with normothermia in man. Fourteen patients treated with TH following cardiac arrest (33–34°C) were compared with eight matched critically ill patients (36–38°C). Continuous infusions of morphine and midazola...

Systems biology has been changing the way biological and biotechnological research is performed. Now, systems biological approaches can be taken to develop bioprocesses for the production of valuable drugs, commodity and fine chemicals, fuels, and polymers and other materials; this is termed systems biotechnology. Here I present the general strategies for systems biotechnology and several examp...

Systems biology has been changing the way biological and biotechnological research is performed. Now, systems biological approaches can be taken to develop bioprocesses for the production of valuable drugs, commodity and fine chemicals, fuels, and polymers and other materials; this is termed systems biotechnology. Here I present the general strategies for systems biotechnology and several examp...

Breast cancer (BC) is the foremost cause of cancer-related mortality in women worldwide. An increasing number of studies has confirmed that microRNAs (miRNAs or miRs) play an important role in the development and progression of BC. microRNA-214 (miR-214), a member of the miRNA family, has been demonstrated to function as both a tumor suppressor and oncogene in various types of human cancer. How...

Background & Aims: An abstract is the best source of information within a content. The structured abstract is the best representation of the main source. Writing an appropriate abstract requires adherence to standards of abstracting. The aim of this study wasto investigate the compliance of Persian abstracts of research papers in medical journals of universities of medical sciences (type 1) wit...