General transcription factor TFIID consists of TATA box-binding protein (TBP) and TBP-associated factors (TAF(II)s), which together play a central role in both positive and negative regulation of transcription. The N-terminal region of the 230 kDa Drosophila TAF(II) (dTAF(II)230) binds directly to TBP and inhibits TBP binding to the TATA box. We report here the solution structure of the complex...

http://bmj.com/cgi/content/full/332/7535/230 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/332/7535/230#otherarticles 3 online articles that cite this article can be accessed at: Rapid responses http://bmj.com/cgi/eletter-submit/332/7535/230 You can respond to this article at: http://bmj.com/cgi/content/full/332/7535/230#responses fr...

PREFATORY NOTE........................................................ 228 INTRODUCTION.................................................................................. 229 RESEARCH ON TRANSFORMATION................................................................ 229 Strains....................................................................................... 230 Media...........................

Thermodynamic stability and unfolding kinetics of proteins are typically determined by monitoring protein unfolding with spectroscopic probes, such as circular dichroism (CD) and fluorescence. UV absorbance at 230nm (A(230)) is also known to be sensitive to protein conformation. However, its feasibility for quantitative analysis of protein energetics has not been assessed. Here we evaluate A(23...

Experimental Biology and Medicine Nurbay Ates, Gul Ilbay and Deniz Sahin Application Suppression of Generalized Seizures Activity by Intrathalamic 2-Chloroadenosine 2005, 230:501-505. Experimental Biology and Medicine http://ebm.rsmjournals.com/content/230/7/501 Updated information and services can be found at: http://ebm.rsmjournals.com/content/230/7/501#BIBL This article cites 34 articles, 4 ...

Experimental Biology and Medicine Charlotte Atkinson, Cara L. Frankenfeld and Johanna W. Lampe to Human Health Gut Bacterial Metabolism of the Soy Isoflavone Daidzein: Exploring the Relevance 2005, 230:155-170. Experimental Biology and Medicine http://ebm.rsmjournals.com/content/230/3/155 Updated information and services can be found at: http://ebm.rsmjournals.com/content/230/3/155#BIBL This ar...

Human identification (ID) is a biometric task, comparing single input sample to many stored templates to identify an individual in a reference database. This paper aims to present the perspectives of personalized heartbeat pattern for reliable ECG-based identification. The investigations are using a database with 460 pairs of 12-lead resting electrocardiograms (ECG) with 10-s durations recorded...