The major adduct formed on acid hydrolysis of calf thymus DNA which has been reacted with 8,9-dichloro-8,9-dihydroaflatoxin B1, a chemical model of the ultimate carcinogen 8,9-dihydro-8,9-epoxyaflatoxin B1 (AFB1-epoxide), has been characterized by proton nuclear magnetic resonance and fast atom bombardment mass spectroscopy. This adduct has been identified as an N7-substituted guanine adduct an...

The title compound, C(23)H(24)Cl(2)O(3), was synthesized by reaction of 2,4-dichloro-benzaldehyde and 5,5-dimethyl-cyclo-hexane-1,3-dione in ethyl-ene glycol. The central ring of the xanthene moiety is almost planar (with an r.m.s. deviation of 0.0268 Å from the least-squares plane) while the two outer rings, in a cis arrangement, display envelope conformations. The ring of the 2,4-dichloro-phe...

The conformation of the N-H bond in the title compound (23DCPCA), C(8)H(6)Cl(3)NO, is syn to both the 2- and 3-chloro substituents in the aromatic ring, similar to the 2-chloro substituent in 2-chloro-N-(2-chloro-phen-yl)acetamide (2CPCA), the 2- and 3-chloro substituents in N-(2,3-dichloro-phen-yl)acetamide (23DCPA) and in 2,2-dichloro-N-(2,3-dichloro-phen-yl)acetamide (23DCPDCA). The bond par...

principle that most of us are linked by short chains of acquaintances — was first investigated as a question in sociology and is a feature of a range of networks arising in nature and technology. Experimental study of the phenomenon revealed that it has two fundamental components: first, such short chains are ubiquitous, and second, individuals operating with purely local information are very a...

principle that most of us are linked by short chains of acquaintances — was first investigated as a question in sociology and is a feature of a range of networks arising in nature and technology. Experimental study of the phenomenon revealed that it has two fundamental components: first, such short chains are ubiquitous, and second, individuals operating with purely local information are very a...

principle that most of us are linked by short chains of acquaintances — was first investigated as a question in sociology and is a feature of a range of networks arising in nature and technology. Experimental study of the phenomenon revealed that it has two fundamental components: first, such short chains are ubiquitous, and second, individuals operating with purely local information are very a...

principle that most of us are linked by short chains of acquaintances — was first investigated as a question in sociology and is a feature of a range of networks arising in nature and technology. Experimental study of the phenomenon revealed that it has two fundamental components: first, such short chains are ubiquitous, and second, individuals operating with purely local information are very a...

Screening of estrogenic activity on dichloro diphenyl trichloroethane (DDT), dichloro diphenyl dichloro ethylene (DDE), dieldrin, heptachlor, aldrin, chlordane, lindane, polybrominated diphenyl ethers (PBDE) and parabens was compared using Organization for Economic Cooperation and Development (OECD) test guideline 455 (TG455). The estrogenic activity of DDT was 58,000-fold (PC50, 1.67 × 10(-6) ...