Abstract Background and Aims Albuminuria in patients with diabetes presents a higher risk for adverse renal cardiovascular (CV) outcomes. Sodium-glucose co-transporter 2 (SGLT2) inhibitors demonstrate improved albuminuria reduces the of end-stage disease chronic kidney disease. The study aim was impact SGLT2 inhibitor dapagliflozin on urine albumin-to-creatinine ratio (UACR) GFR decline. Method...

it is now generally recognized that anaerobic bacteria may be involved in most human bacterial infections that follow any form of surgery or are related to those body sites that have a large anaerobic population. anaerobes must therefore be sought in a wide variety of clinical specimens. in this study, 3015 specimens of patients (1684 male and 1331 female) with periodontitis (160 cases), abcess...

Peter A. Vanrolleghem , Gurkan Sin, Stijn W.H. Van Hulle, Dirk J.W. De Pauw, Ann van Griensven BIOMATH, Department of Applied Mathematics, Biometrics and Process Control, Ghent University, Coupure Links 653, B-9000 Gent, Belgium modelEAU, Département de génie civil, Pavillon Pouliot, Université Laval, Québec, Qc, Canada G1K 7P4 PIH, Department of Industrial Engineering and Technology, Hogeschoo...

Van Baalen, C.A., C. Els, L. Sprong, R. van Beek, E. van der Vries, A.D.M.E. Osterhaus 6 and G.F. Rimmelzwaan 7 1 Viroclinics Biosciences, Rotterdam, The Netherlands; 2 Erasmus MC Department of 8 Viroscience, Rotterdam, The Netherlands. 9 10 # Address correspondence to: [email protected] 11 12 Institutional addresses: 13 Viroclinics Biosciences; Marconistraat 16; 3029 AK Rotterdam; The Net...

Michael Brecht,1 Michale S. Fee,2 Olga Garaschuk,3 Fritjof Helmchen,4 Troy W. Margrie,6 Karel Svoboda,7 and Pavel Osten5 1Department of Neuroscience, Erasmus Medical Center, University Medical Center Rotterdam, 3015 DR Rotterdam, The Netherlands, 2Department of Brain and Cognitive Sciences, McGovern Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, 3Institute of ...

New lessons on the Sudd hydrology learned from remote sensing and climate modeling Y. A. Mohamed, H. H. G. Savenije, W. G. M. Bastiaanssen, and B. J. J. M. van den Hurk UNESCO-IHE, P.O. Box 3015, 2601 DA Delft, The Netherlands Delft University of Technology, Stevinweg 1, 2628 CN Delft, The Netherlands ITC (currently with WaterWatch), Generaal Foulkesweg 28, 6703 BS Wageningen, The Netherlands K...

We present a new technique for determining an upper limit for the mass of the black hole in active galactic nuclei showing warm absorption features. The method relies on the balance of radiative and gravitational forces acting on outflowing warm absorber clouds. It has been applied to 6 objects: five Seyfert 1 galaxies: IC 4329a, MCG−6-3015, NGC 3516, NGC 4051 and NGC 5548; and one radio-quiet ...

Reverse cochlear propagation in the intact cochlea of the gerbil: evidence for slow 1 traveling waves. 2 3 4 Sebastiaan W. F. Meenderink & Marcel van der Heijden 5 6 Department of Neuroscience, Erasmus MC, Dr. Molewaterplein 50, 3015 GE 7 Rotterdam, the Netherlands 8 9 Running head: Reverse propagation in the cochlea 10 11 Contact information: 12 S.W.F. Meenderink; Erasmus MC, Department of Neu...

STAT1 is activated by IFNs and other cell signals. Following activation, STAT1 is translocated to the nuclei and activates transcription of IFN-stimulated genes. Although the activation of STAT1 by IFNs is classically associatedwith antiviral defense and tumor-suppressive functions, emergingdata indicate that expressionof the STAT1 pathway confers cellular resistance to DNA-damaging agents and ...