نتایج جستجو برای: 326 and 298

تعداد نتایج: 16828898  

Journal: :Neuro-oncology 2015
Wenzhong Du Xing Liu Lingchao Chen Zhijin Dou Xuhui Lei Liang Chang Jinquan Cai Yuqiong Cui Dongbo Yang Ying Sun Yongli Li Chuanlu Jiang

BACKGROUND Few studies have associated microRNAs (miRNAs) with the hedgehog (Hh) pathway. Here, we investigated whether targeting smoothened (SMO) with miR-326 would affect glioma biological behavior and stemness. METHODS To investigate the expression of SMO and miR-326 in glioma specimens and cell lines, we utilized quantitative real-time (qRT)-PCR, Western blot, immunohistochemistry, and fl...

Journal: :Pediatric Critical Care Medicine 2018

Journal: :The Mathematical Gazette 1909

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Benjamin Kefas Laurey Comeau Desiree H Floyd Oleksandr Seleverstov Jakub Godlewski Tom Schmittgen Jinmai Jiang Charles G diPierro Yunqing Li E Antonio Chiocca Jeongwu Lee Howard Fine Roger Abounader Sean Lawler Benjamin Purow

Little is known of microRNA interactions with cellular pathways. Few reports have associated microRNAs with the Notch pathway, which plays key roles in nervous system development and in brain tumors. We previously implicated the Notch pathway in gliomas, the most common and aggressive brain tumors. While investigating Notch mediators, we noted microRNA-326 was upregulated following Notch-1 knoc...

Journal: :International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992
K P Plotzke T Haradahira L Stancato N M Olken S Skinner M D Gross R L Wahl R E Counsell

We have designed and synthesized two radioiodinated analogs of hexadecylphosphocholine in order to evaluate their tumor imaging potential. 12-(m[125I]iodophenyl)dodecyl phosphocholine (NM-324) and hexadecyl-2-[N,N-dimethyl-N-(m[125I]iodobenzyl)-ammonium] ethyl phosphate (NM-326) demonstrated the ability of such compounds to localize in and thereby visualize the Walker 256 tumor in rats. However...

Journal: :Bacteriological reviews 1974
P M Blumberg J L Strominger

INTRODUCTION ........................................................ 291 General ............... ......................................... 291 Cell Waill Structure and Synthesis ....................... ........................ 292 Identification of the Target of Penicillin Action .......... ........................ 293 PENICILLIN-BINDING COMPONENTS .............. .......................... 296...

Journal: :BMJ 2003
Didier Fassin Helen Schneider

http://bmj.com/cgi/content/full/326/7387/495 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/326/7387/495#otherarticles 3 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/326/7387/495#BIBL This article cites 14 articles, 2 of which can be accessed free at: Rapid responses http://bmj.com/cgi/ele...

1980
WILLIAM A SCOTT JOANNE M ZRIKE ANNE L HAMILL JENNIFER KEMPE ZANVIL A COHN

During the course o f our studies on the lipid composition o f macrophage membranes, it was noted that 25% of the total fatty acid content of this cell was composed of arachidonie acid (20:4)) Similar values have been reported for both rabbit (1) and h u m a n mononuclear phagocytes (2), whereas the fatty acid complement of most other cell types rarely exceeds a few percent. This unusual enrich...

2015
Shifang Yu Huicong Huang Gang Deng Zuoting Xie Yincai Ye Ruide Guo Xuejiao Cai Junying Hong Dingliang Qian Xiangjing Zhou Zhihua Tao Bile Chen Qiang Li

Platelets play crucial roles in hemostasis, thrombosis, wound healing, inflammation, angiogenesis, and tumor metastases. Because they are anucleated blood cells, platelets lack nuclear DNA, but they do contain mitochondrial DNA, which plays a key role in regulating apoptosis. Recent evidence has suggested that miRNAs are also involved in regulating gene expression and apoptosis in platelets. Ou...

Journal: :BMJ 2003
David Prideaux

http://bmj.com/cgi/content/full/326/7383/268 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/326/7383/268#otherarticles 6 online articles that cite this article can be accessed at: Rapid responses http://bmj.com/cgi/eletter-submit/326/7383/268 You can respond to this article at: http://bmj.com/cgi/content/full/326/7383/268#responses at...

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