OBJECTIVE Published research has not considered acute diseases and injuries in assessing the impact of varying disease counts on health-related quality of life (HRQoL). We used Chinese value sets of EQ-5D-3L to examine the relationship between the number of diseases individuals had (including chronic diseases, acute diseases and injuries) and their HRQoL. METHODS A total of 19 387 individuals...

BACKGROUND The EQ-5D is a brief, generic measure of health status that can be easily incorporated into population health surveys. There are two versions of the EQ-5D for use in adult populations, one with 3 response levels in each of the instrument's 5 dimensions (EQ-5D-3L) and one with 5 levels in each dimension (EQ-5D-5L). We compared the two versions as measures of self-reported health statu...

BACKGROUND Most previous studies concerning the validity of the EQ-5D-3L items refer to applications of only a single language version of the EQ-5D-3L in only one country. Therefore, there is little information concerning the extent to which the results can be generalised across different language versions and/or different countries. Here the validity of the EQ-5D-3L items is investigated for s...

A hierarchical optimisation strategy has been introduced for minimising the Hartree-Fock/Kohn-Sham energy, consisting of three levels (3L): an atom-in-a-molecule optimisation, a valence-basis molecular optimisation, and a full-basis molecular optimisation. The density matrix formed at one level is used as a starting density matrix at the next level with no loss of information. To ensure a fast ...

objective(s): nowadays, cancer is an important public health problem in all countries. limitations of current chemotherapy for neoplastic diseases such as severe adverse reactions and tumor resistance to the chemotherapeutic drugs have been led to a temptation for focusing on the discovery and development of new compounds with potential anticancer activity.   materials and methods: a new series...

In the context of general demand cost sharing, we present the first group-strategyproof mechanisms for the metric fault tolerant uncapacitated facility location problem. They are (3L)-budget-balanced and (3L · (1 +Hn))-efficient, where L is the maximum service level and n is the number of agents. These mechanisms generalize the seminal Moulin mechanisms for binary demand. We also apply this app...

1. Definitions and general properties. Let X be a compact topological space. Definition 1. For any open cover 31 of X let N(ñ) denote the number of sets in a subco ver of minimal cardinality. A subco ver of a cover is minimal if no other subcover contains fewer members. Since X is compact and 31 is an open cover, there always exists a finite subcover. To conform with prior work in ergodic theor...

Three-phase three-level dual-active-bridge (3L-DAB3) converters are a potential topology for high-voltage and high-power applications. Neutral-point voltage balancing is complex important issue (3L) circuits. Compared with the single-phase 3L converter, self-balancing capability of 3L-DAB3 limited. To guarantee reliability neutral-point method proposed in this paper. First, principle analyzed. ...