Oligomannoses are evolutionarily the oldest class of N-glycans, where arms common pentasaccharide unit, i.e., Man?(1–6)-[Man?(1–3)]-Man?(1–4)-GlcNAc?(1–4)-GlcNAc?1-Asn, functionalized exclusively with branched arrangements mannose (Man) monosaccharide units. In mammalian species oligomannose N-glycans can have up to 9 Man; meanwhile structures grow over 200 units in yeast mannan. The highly dyn...

A 66-year-old man presents with bulging and persistent burning pain in the right abdominal side for 4 days.

The major glycosylphosphatidylinositols (GPIs) transferred to protein in mammals and trypanosomes contain three mannoses. In Saccharomyces cerevisiae, however, the GPI transferred to protein bears a fourth, alpha1,2-linked Man on the alpha1,2-Man that receives the phosphoethanolamine (EthN-P) moiety through which GPIs become linked to protein. We report that temperature-sensitive smp3 mutants a...

A fucoidan extracted from Saccharina japonica was fractionated by anion exchange chromatography. The most complex fraction F0.5 was degraded by dilute sulphuric acid and then separated by use of an activated carbon column. Fraction Y1 was fractionated by anion exchange and gel filtration chromatography while Fraction Y2 was fractionated by gel filtration chromatography. The fractions were deter...