A study of the effect of the tetrazole moiety, a cis-amide bond surrogate, on the Cu(II) coordinating properties of oligopeptides is reported. Insertion of the tetrazole moiety Psi[CN(4)] into the peptide sequence of [D-Ala(2)]deltorphin I changes considerably the coordination ability of the peptide. Potentiometric and spectroscopic results show that if the tetrazole moiety is in a suitable pos...

 In this article, synthesis of the explosive synthesis of 5- picrylamino-1, 2, 3, 4-tetrazole (PAT) from the reaction of 5-amino-1, 2, 3, 4-tetrazole with picryl chloride in different conditions of temperature, with density functional theory method were studied. For this purpose, at first the material contained in the both sides of reaction were geometrically optimized, then th...

The ongoing study is a Ugi-azide four-component reaction for the synthesis of 1,5-disubstituted tetrazole(1,5-DST), which involves an aldehyde, different amines, isocyanides, and as azide’s source Trimethylsilylazide (TMSN3), in water solvent using catalyst tetradecyltrimethylammonium bromide (TTAB) with load (10% mole), provides hydrophobic micellar site. This approach step toward green chemis...

Purpose: The article is aimed to synthesize,characterize and screening the biological activity of a series of Synthesis of 1-(2-(3-(3-chloro-1-(4-substituted phenyl)-4-tetrazole-2-yl)-1H-indol-1-yl)acetyl)-4-(2-(4substituted phenyl)hydrazono)-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one 4(a-f). Indole-3-carbaldehyde and chloro ethyl acetate were dissolved in DMF. To this reaction mixture anhydrous ...

The green synthesis of 5-(4-aminophenyl)-4-aryl-4H-1,2,4-triazole-3-thiol was achieved in four steps, In first step, 4-amino benzoic acid refluxed in ethanol along with catalyst Conc. Sulphuric acid to produce ethyl-4-amino benzoate I. Further compound I refluxed with hydrazine hydrate in ethanol to produce 4-amino benzohydrazide II. Compound II refluxed in ethanolic potassium hydroxide with ca...

Three novel tetrazole-based frustrated magnets, namely, Co3(OH)2(3-ptz)2(SO4)(H2O)4 (1), Co2(OH)(tzba)(H2O)4 (2) and [Co(OH)(tta)] (3) (3-ptz = 5-(3-pyridyl) tetrazole, H2tzba = 4-(1H-tetrazol-5-yl) benzoic acid, Htta = 1H-tetrazole) were hydrothermal synthesized and magnetically characterized. Compound 1 is a 2D (4,4) layered structure assembled by sulfate capped triangular [Co3(μ3-OH)(μ3-SO4)...

Absorption and fluorence spectra of a series of 5-phenyltetrazole derivatives have been measured. Compounds carrying electron-accepting CN or CÖOH groups in the phenyl ring exhibit dual fluorescence. Investigations carried out in acid and basic media and a comparison of the fluorescence of p-cyano-5-phenyltetrazole and l-methyl-5-(4'-cyano) phenyltetrazole show the anions of respective 5-phenyl...