Abstract In this paper we present the distribution of molecular gas in Milky Way Galactic plane from l = [59.75, 74.75]° and b [−5.25, +5.25]°, using MWISP 12 CO/ 13 CO/C 18 O emission-line data. The region can be mainly attributed to Local Spur, Arm, Perseus arm, Outer arm. Statistics physical properties each such as excitation temperature, optical depth, column density, are presented. Using D...

BACKGROUND The Diabetes Prevention Program (DPP) is highly effective in promoting weight loss in overweight and obese individuals. However, one-on-one DPP sessions are costly. As a cost-saving alternative, a group version of the DPP, called Group Lifestyle Balance program (GLB), has been developed but has been shown to be less effective. The aim of this two-arm parallel randomized controlled tr...

Objectives To determine if a diabetes prevention program (DPP) delivered by a commercial weight management provider using a UK primary care referral pathway could reduce the progression to type 2 diabetes (T2D) in those diagnosed with non-diabetic hyperglycemia (NDH-being at high risk of developing T2D). Research design This is a quasi-experimental translational research study. Methods 14 p...

Aronia berries have many potential effects on health, including an antioxidant effect, effect for antimutagenesis, hepatoprotection and cardioprotection, an antidiabetic effect and inhibition of cancer cell proliferation. Previous human studies have shown that aronia juice may be useful for treatment of obesity disorders. In this study, we found that aronia juice has an inhibitory effect agains...

Economic interactions are conducted between economic agents individuals and collectives, through exchange of natural or artificial entities goods, services and money, in a myriad of combinations. In this article we adopt a microscopic point of view, concentrating on the exchanged entities, and extracting their relevant attributes as seen from structurally simple economic processes. Following th...

Abhijit A. Raut and Bhavin Jankharia Introduction . . . . . . . . . . . . . . . . . . . . 35 Imaging Modalities . . . . . . . . . . . . . . . . . 36 Development of Paranasal Sinuses . . . . . . . . . . 36 Anatomy . . . . . . . . . . . . . . . . . . . . . . 37 Mucociliary Apparatus . . . . . . . . . . . . . . . 38 Normal Nasal Variants . . . . . . . . . . . . . . . 38 Sinonasal Disease . . . . ....

Dipeptidyl peptidase-4 (DPP-4) inhibitors prevent degradation of incretin hormones (glucagon-like peptide 1 [GLP-1] and glucose-dependent insulinotropic polypeptide [GIP]), whereas metformin may increase GLP-1 levels. We examined, in a four-period crossover trial, the influence of metformin (2,000 mg/day), sitagliptin (100 mg/day), or their combination, on GLP-1 responses and on the incretin ef...

The extent to which a drug inhibits a target responsible for a therapeutic effect is a more rational primary endpoint for dose-finding studies of more selective anticancer drugs than the conventional endpoint of dose-limiting toxicity (DLT) used for cytotoxic agents. An adaptive phase I trial design incorporating maximum target inhibition as the primary endpoint was developed to define the opti...