total protein and dna extracted from histologically diagnosed normal nonmalignant and esophageal tumor tissues were used for analysis of polypeptides pattern by two-dimensional gel electrophoresis and dna transforming activity in nih 3t3 cell transfection assay, respectively. in comparison to normal tissues, eight polypeptides underwent down-regulation or disappeared, while seven polypeptides w...

to solve the geodetic boundary-value problem the gravity anomalies have to be continued from the earth's surface down onto the geoid surface. helmert’s gravity anomalies (multiplied by the geocentric radius) are harmonic above the geoid. it is thus possible to use them in the poisson solution of the inverse dirichlet boundary value problem to get their values on the geoid. the downward con...

the innate immune system utilizes pattern recognition receptors (prrs) to recognize microbes. pathogens contain various molecules with diverse effects on immune response. in this study, we evaluated the effect of dna and protein components derived from two intracellular microorganisms including listeria monocytogenes (l.monocytogenes) and toxoplasma gondii (t. gondii) on dendritic cells (dcs) a...

OBJECTIVE Interaction of stromal and tumor cells plays a dynamic role in initiating and enhancing carcinogenesis. In this study, we investigated the crosstalk between colorectal cancer (CRC) cells with stromal fibroblasts and the anti-cancer effects of curcumin and 5-Fluorouracil (5-FU), especially on cancer stem cell (CSC) survival in a 3D-co-culture model that mimics in vivo tumor microenviro...

this study examined the effect of the zpd-based discourse scaffolding on efl learners' co-construction of l2 metadiscourse performing collaborative writing tasks and explored the discourse scaffolding dynamics. the participants were 160 efl students that were assigned to four different treatment conditions: (i) formal teaching, (ii) input enhancement, (iii) non-zpd interaction, and (iv) zpd-bas...