A recombinant replication-defective adenovirus expressing the major epitopes of porcine circovirus-2 (PCV-2) capsid protein (rAd/Cap/518) was previously constructed and shown to induce mucosal immunity in mice following intranasal delivery. In the present study, immune responses induced by intranasal immunization with a combination of rAd/Cap/518 and cytosine-phosphate-guanosine oligodeoxynucle...

, 682 (2003); 299 Science et al. M. J. Levene Concentrations Zero-Mode Waveguides for Single-Molecule Analysis at High This copy is for your personal, non-commercial use only. clicking here. colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others here. following the guidelines can be obtained by Permission to republish ...

2077 Background: We have previously shown that the cytosine analog CS-682 is active in orthotopic metastatic nude mouse models of human pancreatic cancer. The current study evaluates CS-682 in a novel adjuvant-treatment orthotopic nude mouse model of human pancreatic cancer with efficacy visualized in real-time with fluorescence imaging. METHODS Seven days after implantation, mice were random...

We assessed phytoplankton dynamics in three lakes in the Greater Yellowstone Ecosystem to better understand the connections between changing environmental conditions and aquatic communities. This work primarily describes the connections between resource availability and phytoplankton seasonal succession in these lakes. We hypothesized that algal species efficient at utilizing a given resource (...

The epidemiology of animal rabies in the region of Araçatuba, in the northwest of São Paulo State, from 1993 to 2007, is described according to the results from diagnoses made at laboratories in the region, using the fluorescent antibody and mouse inoculation tests. Out of 10,579 samples analyzed, 4.9% were positive (518/10,579). Dogs accounted for 67% of the cases (346/518) and these occurred ...

The Mössbauer effect was first described by Rudolf Mössbauer in 1957. The effect describes how nuclei can emit or absorb gamma-rays without recoiling under certain circumstances. When a free nuclei emits or absorbs gamma-rays, it recoils as a result of energy and momentum conservation. As a result, if a free nucleus undergoes a transition from an excited state to its ground state by emitting ga...

INTRODUCTION Recent data indicates that low vitamin D (25(OH)D) levels can lead to a worst prognosis in HIV-infected individuals, even in those on successful antiretroviral therapy (ART) [1]. Portugal is the European country that has the largest average sun exposure time but prevalence of hypovitaminosis D is mostly unknown. Our aim was to determine the prevalence of hypovitaminosis D in HIV pa...

Some big problems for students studying heat transfer are (1) difficulty in visualizing both basic and complex theoretical concepts, (2) unsure how to design changes effect heat flow or temperature distributions, (3) unclear how to apply theoretical concepts in the development of components / systems and (4) confusion with how to extend single point experiments to generic applications. It is im...

To evaluate the clinical feasibility of the antibody titer against a chimeric polypeptide (named Core 518), in which a domain of Core and NS3 of hepatitis C virus (HCV) was fused, ELISA was performed in a total of 76 serum samples. Each serum was serially diluted using two-fold dilution method with distilled water into 10 concentrations. They were all positive for second generation anti-HCV ass...