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4 5 Liya Wang*, Ren Sun and Staffan Eriksson 6 Department of Anatomy, Physiology and Biochemistry, Section of Veterinary Medical 7 Biochemistry, SLU, The Biomedical Centre, P.O. Box 575, SE-751 23 Uppsala, Sweden 8 9 10 * Corresponding author: Tel: 46 18 471 4119; 11 Fax: 46 18 550762 12 e-mail: [email protected] 13 14 15 Running title: Thymidine kinase 2 and antiviral thymidine analogs. 16 Copy...

Trametinib is a MEK1 inhibitor used in the treatment of BRAF V600E or V600K mutated melanoma. Roughly 10% patients develop cardiomyopathy following chronic trametinib exposure. Although described clinically, molecular landscape trametinib-induced heart failure has not been characterized. We hypothesized that promotes widespread transcriptomic changes consistent with drug-induced cardiotoxicity....

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Correspondence : Krishna Prasad D. Professor & H.O.D, Department of Prosthodontics, A.B. Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore 575 018, India. E-mail : [email protected] Abstract: Bruxism, which can be considered as an umbrella term for clenching and grinding of teeth, is the commonest of the many parafunctional activities of the stomatognathic system...

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Received May 31, 2016. Revised June 24, 2016. Accepted June 27, 2016. Correspondence to: Sukumar Shanmugam Department of Neuro-Physiotherapy, Nitte Institute of Physiotherapy, Deralakatte, Mangalore, Karnataka 575 018, India Tel: +91-824-2202443, Fax: +91-824-2202443, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Com...