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cial problems affecting the skin and nails, to deeply invasive and disseminated infections, such as systemic candidiasis and pulmonary aspergillosis. These illnesses reduce the quality of life of patients and can progress to become life threatening. Four classes of antifungal drugs are available at present: polyene macrolides, azoles, flucytosine and candins. However, their use is restricted by...
Subtilase cytotoxin (SubAB) from verotoxin (VT)-producing Escherichia coli (VTEC) strains was first described in the 98NK2 strain and has been associated with human disease. However, SubAB has recently been found in two VT-negative E. coli strains (ED 591 and ED 32). SubAB is encoded by two closely linked, cotranscribed genes (subA and subB). In this study, we investigated the presence of subAB...
Transcription factors (TFs) play important roles in plant growth, development, and responses to environmental stress. In this study, we collected 1,455 full-length (FL) cDNAs of TFs, representing 45 families, from wheat and its relatives Triticum urartu, Aegilops speltoides, Aegilops tauschii, Triticum carthlicum, and Triticum aestivum. More than 15,000 T0 TF FOX (Full-length cDNA Over-eXpressi...
Two amino acids (lysine at position 627 or asparagine at position 701) in the polymerase subunit PB2 protein are considered critical for the adaptation of avian influenza A viruses to mammals. However, the recently emerged pandemic H1N1 viruses lack these amino acids. Here, we report that a basic amino acid at position 591 of PB2 can compensate for the lack of lysine at position 627 and confers...
The skin dermis evolves from a multipotent pool of fibroblasts, which differentiate into distinct subpopulations creating the different dermal layers and respective architecture. This maturation process is governed by tight balance fibroblast proliferation, quiescence extracellular matrix (ECM) deposition. During wound healing, quiescent fibroblasts restart proliferating, migrate bed deposit EC...
BACKGROUND Gastric banding is a safe and efficient bariatric procedure. We report here the results of 591 consecutive gastric bandings in terms of excess weight loss with up to 10 years follow-up and the complications. METHODS Between June 1996 and September 2006, 591 patients underwent laparoscopic adjustable gastric banding (LAGB) by the same surgeon (JB). Of these patients, 69.2% were wome...
The surface protein SdrE, a microbial surface components recognizing adhesive matrix molecule (MSCRAMM) family protein expressed on the surface of Staphylococcus aureus (S. aureus), can recognize human complement regulator Factor H and C4BP, thus making it a potentially promising vaccine candidate. In this study, SdrE278-591 was found to directly affect S. aureus host cell invasion. Additionall...
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1. Ihnatowicz P, Wątor Drywień EM. Supplementation in Autoimmune Thyroid Hashimoto’s Disease. Vitamin D and Selenium. J Food Nutr Res. 2019;7(8):584–591. doi:10.12691/jfnr-7-8-6. http://www.sciepub.com/JFNR/ab.... CrossRef Google Scholar
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