BACKGROUND Prostate-specific antigen (PSA) assays have historically produced different results. Our aim was to investigate the comparability of assay results of selected commercially available assay methods designed to measure total, free, or complexed PSA (tPSA, fPSA, and cPSA). METHODS We measured tPSA, fPSA, and cPSA in 70 samples and in the WHO PSA 96/670 reference preparation with 6 assa...

www.sciencemag.org (this information is current as of March 5, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/310/5748/670 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/1116739/DC1 can be found at: Su...

The cGMP-dependent protein kinase Ialpha (PKG Ialpha) possesses two functional moieties, the regulatory and catalytic domains, which reside on a single polypeptide chain. Here we report on the influence of the catalytic domain on the binding of cGMP to the regulatory domain. A deletion mutant, delta352-670 of PKG Ialpha, lacking the catalytic domain, was constructed and expressed in E. coli. Th...

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BACKGROUND Human cornea expresses functional Fas-ligand capable of killing Fas+ activated lymphocytes. Fas expression is partly regulated by -670 A/G polymorphism in the promoter region of Fas gene. OBJECTIVE The aim of the present study is to determine the association between Fas-670A/G polymorphism and survival of corneal transplantation. METHODS In 276 graft recipients who mainly underwe...

BACKGROUND The approved immunomodulatory agents for the treatment of multiple sclerosis (MS) are only partially effective. It is thought that the combination of immunomodulatory and neuroprotective strategies is necessary to prevent or reverse disease progression. Irradiation with far red/near infrared light, termed photobiomodulation, is a therapeutic approach for inflammatory and neurodegener...

Testosterone (T) plays a vital role in the sexual function and many other health-related phenomena. We conducted this study to examine the effects of low level laser therapy (LLLT) on the testis in elevating serum T level in rats. We performed the current experimental study using 30 male Sprague-Dawley rats (Orient Bio, Korea) aged six weeks, weighing 200 g. In rats of two laser groups, a 670-n...

background: human cornea expresses functional fas-ligand capable of killing fas+ activated lymphocytes. fas expression is partly regulated by -670 a/g polymorphism in the promoter region of fas gene. objective: the aim of the present study is to determine the association between fas-670a/g polymorphism and survival of corneal transplantation. methods: in 276 graft recipients who mainly underwen...