نتایج جستجو برای: 7ra
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H(a) is h times a generator of wr2,.(S2t1-). Thus Hmay be regarded as.a generalization of. the Hopf invariant. Let R,1 be the rotation group of SI-', 7r the mapping of RT_i into SIwhich sends each rotation r into the image under r of a fixed point yo e St-'. If p < 2r 2 andf is a mapping of SP-1 into R, 1, thenf defines a mapping F: SPX SI -I SI-' of type (7ra, 1), where a is the element of 7rp...
Abstract BACKGROUNDS Perianal fistulas occur in ~30-40% of patients associated with high morbidity and an impaired quality life. The management perianal fistulizing CD is a major clinical challenge, where its underlying etiology poorly understood. METHODS We recruited history of: 1) fistulas; 2) without involvement; 3) idiopathic fistulas. Biopsies were taken from the fistula tracts, external o...
Homeostatic control of the immune system involves mechanisms that ensure the self-tolerance, survival and quiescence of hema-topoietic-derived cells. In this study, we demonstrate that the GTPase of immunity associated protein (Gimap)5 regulates these processes in lymphocytes and hematopoietic progenitor cells. As a consequence of a recessive N-ethyl-N-nitrosourea–induced germline mutation in t...
The cytokine thymic stromal lymphopoietin (TSLP) is produced by epithelia exposed to the contact sensitizer dibutyl phthalate (DBP), and it is critical for the induction of Th2 immune responses by DBP-FITC. TSLP is thought to act on dendritic cells (DC), but the precise DC subsets involved in the response to TSLP remain to be fully characterized. In this study we show that a subset of CD326 lo ...
In adaptive immunity, Th17 lymphocytes produce the IL-17 and IL-22 cytokines that stimulate mucosal antimicrobial defenses and tissue repair. In this study, we observed that the TLR5 agonist flagellin induced swift and transient transcription of genes encoding IL-17 and IL-22 in lymphoid, gut, and lung tissues. This innate response also temporarily enhanced the expression of genes associated wi...
During an immune response, most effector T cells die, whereas some are maintained and become memory T cells. Factors controlling the survival of effector CD4 + and CD8 + T cells remain unclear. In this study, we assessed the role of IL-7, IL-15, and their common signal transducer, STAT5, in maintaining effector CD4 + and CD8 + T cell responses. Following viral infection, IL-15 was required to m...
Compare to autologous NK cells, allogeneic NK cells have more anti-tumor cytotoxicity without GVHD. Adoptive transfer of allo-reactive NK cell can be ideally used combined with other immunotherapy. However, in vivo persistency of transferred NK cells in the recipients are still an obstacle in NK cell-based immunotherapy. As most of NK cells purified from peripheral blood of donors are fully dif...
Let D be a plane domain partly bounded by two line segments which meet at the origin and form there an interior angle va > 0. Let U(x, y) be a solution in D of Poisson's equation such that either U or dll/dn (the normal derivative) takes prescribed values on the boundary segments. Let U(x, y) be sufficiently smooth away from the corner and bounded at the corner. Then for each positive integer N...
On the basis of an expression given by Buchholz for the magnetic-vector potential for an infinitely long twisted-wire pair, the expressions for the external component-flux densities in cylindrical coordinates have been developed. These expressions checked very well with data obtained in the proximity of precisionwound twisted-wire pairs. A generalized graph for various radii and pitch lengths h...
A potpourri of Skyrme-model results for the meson-baryon system is surveyed. This talk is devoted to a study of meson-nucleon scattering in skyrmion models of the nucleon. [l”’ We shall focu s o n the characteristic energy-range of the baryon resonances, typically 1.5-2.5 GeV. This is well beyond the point where the chiral Lagrangians are conventionally applied; nor is it known at present how t...
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