CAN J ANESTH 54: 11 www.cja-jca.org November, 2007 to two attempts. After the final spray, the mean visual analogue scores for pain, anxiety and coughing were 7.8 ± 1.3, 6.5 ± 1.7 and 5.2 ± 1.5, respectively (where 0 was described as awful and 10 as enjoyable). All subjects reported the airway spray of lidocaine to have been acceptable; two found it enjoyable. The time from start to final spray...

Introduction Laryngoscopy and tracheal intubation are known to increase sympathetic activity that may be detrimental to patients with preexisting ischaemic or hypertensive heart disease. Aim The aim of this study was to compare of intravenous and oropharyngeal spray of lidocaine and high dose of fentanyl on systolic and diastolic blood pressures and heart rate of patients over 65 years during...

BACKGROUND Tracheal intubation is extremely distressing, painful, and may influence heart rate and blood pressure. Sedatives, analgesics, and muscle relaxants are not commonly used for intubation in neonates. OBJECTIVES This study aimed to evaluate the effects of lidocaine spray as a non-intravenous drug before neonatal intubation on blood pressure, heart rate, oxygen saturation and time of i...

ObjectiveTo evaluate the total toxic dose of lidocaine and serum lidocaine concentrations resulting in clinical signs of toxicity in chickens. DesignExperimental study AnimalsEight healthy, female, 55-week-old chickens (Lohman breed) weighing 1.45 ± 0.17 kg (mean ± SD) ProcedureA loading dose of 2% lidocaine (4 mg/kg) was administered IV, followed by a constant-rate infusion at a dose of 8 mg/k...

Plasma concentrations of lignocaine were measured in three groups of anaesthetized patients following spraying of the trachea and larynx with a lignocaine 10% aerosol spray. Greater venous plasma concentrations occurred in patients who were paralysed with suxamethonium. A mean plasma concentration of 0.1 mug/ml of lignocaine resulted from each 10 mg of lignocaine used in spontaneously breathing...

OBJECTIVE To determine the methods of anesthesia currently being used by pediatric rheumatologists when performing intra-articular corticosteroid injections (IACI). STUDY DESIGN A questionnaire was emailed to all members of the Childhood Arthritis & Rheumatology Research Alliance, a pediatric rheumatology research network in North America. The questionnaire consisted of 11 questions ranging f...

The mechanisms by which lidocaine brings about negative inotropic effects and antiarrhythmic actions in the heart have been examined. Using sheep cardiac Purkinje fibers, we studied the effects of "therapeutic" concentrations of lidocaine (20 microM lidocaine = 5.4 micrograms/ml) on electrical activity, intracellular sodium activity, and tension. For the preparation with a normal, physiological...

background: opiate is used in patient-controlled intravenous analgesia pumps (pcia) for controlling pain in post-surgical patients.other drugs are remarkably added to opioid pumps to enhance quality, lengthen analgesia, and reduce side effects. lidocaine, a local anesthetic which inhibits sodium channels, has anesthetic and analgesic effects when injected locally or intravenously. the objective...

Topical anesthesia for flexible bronchoscopy can be achieved in several ways like administration of an anesthetic agents by injecting through cricothyroid membrane,by giving drug lignocaine through Nebulization, 3}administering the drug through oral spray. Nebulization of lidocaine can achieve very satisfying anesthesia comparable to oral spraying with significant low plasma levels of the drug....