Reduced GABAergic inhibition of kidney-related PVN neurons in streptozotocin1 treated type 1 diabetic mouse 2 3 Yanyan Jiang, Hong Gao, Amanda M. Krantz, Andrei V. Derbenev, Andrea 4 Zsombok 5 6 7 Neuroscience Program, School of Science and Engineering, Tulane University and 8 Department of Physiology, School of Medicine, Tulane University, New Orleans LA, 9 USA 10 11 12 Abbreviated title: Syna...

oxidation of xanthine and hypoxanthine into uric acid, and plays a vital role in producing hyperuricemia and gout. Allopurinol is a clinically used XO inhibitor in the treatment of gout, which blocks the terminal step in uric acid biosynthesis can lower the plasma uric acid concentration. However, due to unwanted side effects of allopurinol, such as hepatitis, nephropathy, and allergic reaction...

techniques that provide firewall-level authentication to ensure authorized access to potentially vulnerable network services. Although these techniques serve as powerful protection mechanism against the intruders, they still suffer from a major problem. The lack of association between the authentication process and the follow-on TCP connection to be established is the most crucial problem still...

than the initial shapes do. By this optimal design method, the algorithm introduced more parameters (twisted angles) for aerodynamic configuration design, and thus demonstrates better of feasibility, robustness, and design outcome for subsonic wing configuration. The resulting outcomes confirm that the method shows quicker in convergence, in comparison to the traditional genetic algorithms.

Collaborative planning, forecasting and replenishment (CPFR) coordinates the various supply chain management activities including production and purchase planning, demand forecasting and inventory replenishment between supply chain trading partners. This study proposes a systematic way of analyzing CPFR supporting factors using fuzzy cognitive map (FCM) approach. FCMs have proven particularly u...

used to address assembly line balancing problems (ALBP), not much attention has been given to the population initialization procedure. In this paper, a comparison is made between a randomly generated initial population and a heuristics-treated initial population. A heuristics-treated population is a mix of randomly and heuristics generated individuals in the initial population. Both populations...

INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 959 R I. FLOURISHING AND ITS OBLIGATIONS . . . . . . . . . . . . . . . . . . . . . . 960 R II. HOW PROPERTY FILLS THE GAP . . . . . . . . . . . . . . . . . . . . . . . . . . 963 R III. CORE AND PERIPHERY IN PROPERTY LAW . . . . . . . . . . . . . . . . . . 971 R A. The Morality of Prope...