UNLABELLED High kidney radiation doses during clinical peptide receptor radionuclide therapy (PRRT) with β-particle-emitting radiolabeled somatostatin analogs will lead to renal failure several months after treatment, urging the coinfusion of the cationic amino acids lysine and arginine to reduce the renal radiation dose. In rat PRRT studies, renal protection by the coadministration of lysine w...

OBJECTIVE To apply a semiquantitative method for analysis of technetium-99m-dimercaptosuccinic acid ((99m)Tc-DMSA) renal scintigraphy for monitoring the effect of extracorporeal piezoelectric lithotripsy (EPL) in patients with calyceal stones on regional kidney function and to check whether EPL had caused any deleterious effect on the target calyceal renal parenchymal function. PATIENTS AND M...

Urinary tract infections are common in children. The available gold standard method for diagnosis, Tc-99m dimercaptosuccinic acid scan is expensive and exposes patients to considerable amount of radiation. This study was performed to compare and assess the efficacy of Power Doppler Ultrasound versus Tc-99m DMSA scan for diagnosis of acute pyelonephritis. A quasi experimental study was conducted...

We report a patient with DTPA and DMSA uptake on unsuspected bone metastases. He had severe pain due to grade 3 hydronephrosis of his left kidney. When Tc-99m DTPA and DMSA renal scanning were performed for preoperative evaluation, abnormal radiopharmaceutical uptake on the iliac area was noted. Pancreatic adenocarcinoma metastases to bone were subsequently defined. This patient is a very demon...

1 Fadime Demir1, Taner Erselcan2, Bülent Turgut3, Zekiye Hasbek3, Perihan Kelkit4, Ayşegül Özdal5, Serdar Savaş Gül6, Pelin Duman7 1Department of Nüclear Medicine, Elazığ Researc and Educational Hospital, Elazığ, 2Nüclear Medicine, Muğla Sıtkı Koçman University, Faculty of Medicine, Muğla, 3Nüclear Medicine, Cumhuriyet University, Faculty of Medicine, Sivas, 4Department of Nüclear Medicine, Siv...

Background: Bone sarcomas are usually aggressive tumors treated by multimodality approaches. Early detection of residual or recurrent tumor tissue after treatment is important in the management of these patients. This is currently achieved by clinical examination, diagnostic radiological procedures, radionuclide imaging techniques and detailed histological examination. Tumor response to preoper...

BACKGROUND The aim of this study was to assess the relation between (99m)Tc-DMSA biodistribution and its reliability as a marker of renal function in patients with glomerular kidney diseases. MATERIAL AND METHODS Sixty-seven patients involved in this study were classified into two groups according to (99m)Tc-DTPA clearance and serum creatinine values: the 1st group consisted of 42 patients wi...

Background: Screening for patients at risk of renal scarring is a challenge in children with acute pyelonephritis (APN). Diuretic Tc-99m mercaptoacetyltriglycine (MAG3) scintigraphy with zero time injection of furosemide (MAG3-F0) was observed to display focal parenchymal disorders. The advantages of MAG3 include: lower radiation dose and short duration of the test. The aim of this study was to...

Introduction:The optimal imaging time of a radionuclide scintigraphy is the time at which the organ of interest has the maximum uptake of the injected radionuclide. This study was performed to investigate the maximum uptake time of 99mTc-DMSA in rat renal scan. Methods: Renal scintigraphy was performed with 3 mCi of 99mTc-DMSA. Planar ima...

There are different scoring systems available for determining the grade of breast cancer malignancy. Breast cancer tumors have been described for grades 1-3 using the modified Nottingham-Bloom-Richardson grading system. Determining the grade is very important for the clinicians to choose the best treatment options. Technetium-99m methoxy isobutyl isonitrile ((99m)Tc-MIBI) and pentavalent (99m)T...