sesame (sesamum indicum l.) seed and oil have long been used widely as healthy foods to supply energy and prevent aging. some of the main active anti-oxidative constituents in sesame seeds are γ-tocopherol and phenols. the purpose of this study was to investigate the relationship between roasting temperature and time with γ-tocopherol and total phenolic compounds (tpc) of sesame seeds when roas...

Background: Previous study by the authors showed that a-tocopherol prevents oxidative stress but would not improve depressed excretory variables in post-obstructed kidney (POK) after release of 24-h unilateral ureteral obstruction (UUO). This study is a supplementary investigation on the effects of a-tocopherol combined with an antagonist of angiotensin-II type-1 (AT1) receptor on renal dysfunc...

Twenty-four crossbred beef cows were used to investigate the concentration of alpha-tocopherol in plasma and tissues following oral administration of four tocopherol sources. Animals were allotted to the following treatments: DL-alpha-tocopherol, D-alpha-tocopherol, DL-tocopheryl acetate and D-alpha-tocopheryl acetate. Animals received a daily oral dose of 1,000 IU of the respective tocopherol ...

Postabsorptive elimination of the various forms of vitamin E appears to play a key role in regulation of tissue tocopherol concentrations, but mechanisms of tocopherol metabolism have not been elucidated. Here we describe a pathway involving cytochrome P450-mediated omega-hydroxylation of the tocopherol phytyl side chain followed by stepwise removal of two- or three-carbon moieties, ultimately ...

this study was performed to investigate the effect of ag+ as an elicitor on the activity of antioxidant enzymes, content of h2o2, accumulation of total tocopherol and antioxidant activity in hairy root cultures of silybum marianum (l.) gaertn. the hairy roots were treated with 2 mm ag+. the treated and non-treated hairy roots were harvested in the same time and data on h2o2 content, dpph, tocop...

Noise induced hearing loss (NIHL) is one of the most important occupational disease worldwide. NIHL has been found potentiate by simultaneous carbon monoxide (CO) exposure. Free radicals have been implicated in cochlear damage resulted from the exposure to noise and due to the CO hypoxia. This study examined whether α-tocopherol administration, as a free radical scavenger, causes the attenuatio...

Noise induced hearing loss (NIHL) is one of the most important occupational disease worldwide. NIHL has been found potentiate by simultaneous carbon monoxide (CO) exposure. Free radicals have been implicated in cochlear damage resulted from the exposure to noise and due to the CO hypoxia. This study examined whether α-tocopherol administration, as a free radical scavenger, causes the attenuatio...

Background: Although the population distribution of serum concentrations of -tocopherol has been described in the United States, little is known about the distribution of -tocopherol or the ratio of -tocopherol to -tocopherol. Objective: Our aim was to describe the distribution of serum concentrations of -tocopherol and -tocopherol in a nationally representative sample of US adults. Design: We ...

Tocopherols are amphipathic antioxidants synthesized exclusively by photosynthetic organisms. Tocopherol levels change significantly during plant growth and development and in response to stress, likely as a consequence of the altered expression of pathway-related genes. Homogentisate phytyltransferase (HPT) is a key enzyme limiting tocopherol biosynthesis in unstressed Arabidopsis leaves (E. C...

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