A 45-year-old woman diagnosed with Wolff-Parkinson-White syndrome preferred treatment with propafenone rather than catheter ablation. A 12-lead electrocardiogram (Fig. 1) after the drug administration showed sinus arrhythmia; alternating ventricular preexcitation; and alternating T wave inversion in the inferior leads during normal AV conduction. Ventricular preexcitation may disappear because ...

Twenty-one patients were studied in whom ventricular preexcitation (VP) had been recorded in the past and had later disappeared, indicating antegrade block in the accessory pathway (AP), either spontaneously (10 patients) or under the effect of chronic treatment with amiodarone (11 patients). VP reappeared in nine cases during vagal stimulation, and in five cases during an i.v. isoproterenol in...

We recorded a discrete 0.95 mV potential consistent with accessory atrioventricular pathway (AP) activation during serial electrophysiologic studies in a patient with Ebstein's anomaly and Wolff-Parkinson-White syndrome. Bipolar pacing from the catheter electrode in which the AP potential was recorded resulted in a stimulus-ventricle interval identical to the AP-ventricle interval during antegr...

* Corresponding author. Department of Int of Medicine and Medical Center, PO Box 11E-mail address: [email protected] (B. Abi-S Peer review under responsibility of Indian H http://dx.doi.org/10.1016/j.ipej.2015.10.005 0972-6292/Copyright © 2015, Indian Heart Rh the CC BY-NC-ND license (http://creativecom coronary sinus will ablate either the atrial insertion on the interatrial septumor the accesso...

Accessory pathway (AP) ablation is one of the most satisfying invasive electrophysiology procedures associated with high success rates and relatively few complications. Nevertheless, when APs are found on the cardiac septum, ablative procedures become complex, and unique pitfalls need to be avoided.These difficulties with septal ablation are magnified in the pediatric population. The relatively...

Transport of proteins through the ALP (alkaline phosphatase) pathway to the vacuole requires the function of the AP-3 adaptor complex and Vps41p. However, unlike other adaptor protein-dependent pathways, the ALP pathway has not been shown to require additional accessory proteins or coat proteins, such as membrane recruitment factors or clathrin. Two independent genetic approaches have been used...

We report a clinical case of a 22-year-old female referred to our institution due to palpitations and preexcitation. Her ECG suggested a right superior paraseptal accessory pathway (AP), which was localised during the electrophysiological study at the superior paraseptal region in close proximity to the His recordings. Reproducible orthodromic reciprocating tachycardia was induced by atrial pac...

BACKGROUND This study describes the use of adenosine during ablation procedures to allow conduction through adenosine-dependent accessory pathways (APs), which are inactive at the time of the procedure. The technique allows for successful mapping and ablation of these pathways. METHODS Retrospective review of all patients undergoing AP ablation from 1998 to 2008 to identify patients with abse...

The transport of newly synthesized proteins through the vacuolar protein sorting pathway in the budding yeast Saccharomyces cerevisiae requires two distinct target SNAP receptor (t-SNARE) proteins, Pep12p and Vam3p. Pep12p is localized to the pre-vacuolar endosome and its activity is required for transport of proteins from the Golgi to the vacuole through a well defined route, the carboxypeptid...

Recurrent or incessant tachycardia is frequently found in symptomatic Wolff-Parkinson-White (WPW) syndrome, leading to ventricular dysfunction, dilated cardiomyopathy (DCM) and heart failure in infants and children. Recently, Winter, et al. report that WPW syndrome could provoke many kinds of cardiac dysfunction, leading to remodeling and progressive ventricular dilatation through pre-excitatio...