Breast Cancer (BC) has associated risk factors and genetic factors like BRCA1, and BRCA2. Many benign and malignant disease processes are found concurrently with BC and believed to be additional risk factors like gall bladder stones (cholelithiasis), hypertension, diabetes mellitus, cerebrovascular lesions, arthritis, spine and spinal cord degenerative lesions, infertility, depression, sleep di...

AAOC: acral angioosteoma cutis BMP: bone morphogenic protein PG: pyogenic granuloma VEGF: vascular endothelial growth factor INTRODUCTION Googe et al in 2006 first described 11 cases of acral angioosteoma cutis (AAOC), characterized by benign vascular and osseous lesions on acral skin. Since then, there have been only 3 additional cases reported. This friable erythematous exophytic papule has c...

Intra- and subcorneal hematoma, a skin alteration seen palmar and plantar after trauma or physical exercise, can be challenging to distinguish from in situ or invasive acral lentiginous melanoma. Thus, careful examination including dermoscopic and histologic assessment may be necessary to make the correct diagnosis. We here present a case of a 67-year-old healthy female patient who presented wi...

Surgical wounds generally heal by primary intention with few complications (Ousey et al, 2011). However, certain patient factors and surgical types may predispose postoperative incisions to skin blistering, particularly if an unsuitable postoperative wound dressing is used. Skin blistering occurs when the epidermis becomes separated from the dermis and results from continued friction on the ski...

The authors present a rare case of double skin tumors: acral lentiginous melanoma and metatypical carcinoma. The tumors were manifested as gradually enlarging ulcerations on the leg and sole of the foot that did not respond to standard treatment. The skin biopsies showed advanced acral lentiginous melanoma on the sole and metatypical carcinoma of the lower leg. Soon after the diagnosis was made...

C utaneous malignant melanoma (MM) falls into two main groups, based on aetiology [1–3]. First, a small minority of patients have acral MM, in which the disease occurs on the palms and soles. The incidence of acral MM is similar in people with widely different skin colours (and hence with different amounts of skin melanin), and at different latitudes. The palms and soles have a thick epidermis,...