PURPOSE A novel end-to-end system using a CCD camera and a scintillator based phantom that is capable of measuring the beam-by-beam delivery accuracy of Robotic Radiosurgery has been developed and reported in our previous work. This work investigates its application to end-to-end type daily QA for Robotic Radiosurgery (Cyberknife) with Variable Aperture Collimator (Iris). METHODS The phantom ...

The treatment of moving tumors with a scanned ion beam is challenging due to interplay effects and changing beam range. We propose multigating, as a method for 4D-treatment optimization and delivery. In 3D beam tracking, tracking vectors are added during delivery to beam spot positions based on the detected motion phase. This has the disadvantage of dose errors in case of complex motion pattern...

From 1997 to 2008 the treatment of more than 400 patients with C ions at the experimental heavy ion treatment facility at GSI has been successfully monitored in vivo and in situ by means of 3D in-beam PET. The promising clinical results of the ion therapy for static tumor entities encourages to apply it to more frequent ones like lung cancer. Due to the sensitivity of the ion range to density c...

in the long-term management of ulcerative colitis patients, repeat dosing maybe required. since 5-asa is largely absorbed from the upper intestine, selective delivery of drugs into the colon may be regarded as a better method of drug delivery with fewer side effects and a higher efficacy. the aim of this study was to prepare and evaluate a double coated multiparticulate system for 5-asa deliver...

this survey was carried out on children less than five years of age from rural areas of three provinces in iran (west azarbaijan, bushehre, and central province), with different health care delivery systems and various types of immunization scheme, to determine the immune status of measles and the vaccine coverage. our results indicate that the rates of measles immunity and vaccine coverage for...

In this paper, simulation codes for Beam Delivery Systems in linear colliders are discussed. Several tracking codes are available for particle tracking. They do not normally include precise calculation of the beam-beam effect, with accounting for pinch, hour-glass, pair production. They provide instead the particle distributions at the interaction point, after tracking through the different com...

The design requirements for current heavy-particle accelerators operated within a hospital to deliver radiation therapy must satisfy both clinical and research needs. Advances in dedicated beam delivery systems for clinical utilization and biological studies add requirements that previous accelerators did not have. Eight years experience using the Loma Linda University proton facility has empha...

PURPOSE Intrafraction rotation of more than 45° and 25° has been observed for lung and prostate tumors, respectively. Such rotation is not routinely adapted to during current radiotherapy, which may compromise tumor dose coverage. The aim of the study was to investigate the geometric and dosimetric performance of an electromagnetically guided real-time dynamic multileaf collimator (DMLC) tracki...