background: because of high morbidity of the brucellosis in humans and the potential use of the microorganism as an agent of biologic warfare, protection of effective vaccines and specific diagnostic reagents become necessary to eradicate brucellosis. objective: in this study we aimed to investigate the cytokine responses and changes in peripheral blood lymphocyte subgroups of acute brucellosis...

background: brucella species can cause infection in a wide range of animals and human beings. oxidative events against brucella infection are not well elucidated. it is possible that brucellosis may be related to increased free radical production and antioxidant depletion. thus, the aim of this study was to determine the total antioxidant capacity (tac) before and after treatment of patients wi...

OBJECTIVE Brucellosis is an endemic zoonosis in Iran. It is a systemic infection that can involve any organs or systems of the body and have variable presentations. Ventriculoperitoneal (VP) shunt infections due to brucellosis have been rarely reported in the literatures. This is the history of a four years old boy who developed Brucella meningoencephalitis at the age of 42 months, whilst he ha...

Background: Brucellosis is a world-wide disease, which has a diverse clinical manifestation, and its diagnosis has to be proven by laboratory data. Serum agglutination test (SAT) is the most-widely used test for diagnosing brucellosis. The enzyme linked immunosorbent assay (ELISA) can also determine specific antibody classes against brucella. It is a sensitive, simple and rapid test, which coul...

Brucellosis is a world-wide zoonosis and systemic disease affecting various organs. The causative organism is an intracellular proteobacteria gram-negative bacillus of the genus Brucella. Human brucellosis is a multi organ disease, transmitted via unpasteurized animal milk and cheese. A renewed scientific interest in human brucellosis has be enfueled by its recent reemergence [1,2]. Symptoms ar...

introduction brucellosis is a common zoonotic disease which has a wide spectrum of clinical manifestations and complications in humans. brucellosis is an endemic disease in iran. the aim of this case report was to introduce acute hepatitis as a rare complication of acute brucellosis. case presentation first case, a 25-year-old man, who complained from fever, chillness, nocturnal sweating, nause...

Brucellosis remains prevalent in developing countries and results in substantial economic losses and human morbidity. The number of brucellosis cases increased in southeast Xinjiang provinces of China in recent years; however, the clinical epidemiological features of brucellosis in here are unclear. In this study, 160 patients with brucellosis in Bazhou People's Hospital between January 2014 an...

CONTEXT Acute pancreatitis can be caused by a variety of infectious agents but it is regarded as an extremely rare complication of brucellosis. CASE REPORT We briefly describe a 56-year-old man who presented with acute pancreatitis, fever, myalgia, and other clinical symptoms. Brucella melitensis was cultured from his blood. All clinical manifestations gradually resolved with the institution ...

Brucellosis is a zoonotic disease that is still endemic in developing countries. Despite early diagnosis and treatment of patients, chronic infections are seen in 10-30% of patients. In this study, we aimed to investigate the immunological factors that play roles in the transition of brucellosis from acute infection into chronic infection. Here, more than 2000 miRNAs were screened in peripheral...

In this report we describe a patient with sub-acute bacteremic brucellosis complicated by Brucella parotitis with abscess formation as a paradoxical reaction on therapy. A 69 years old male known to have Warthin’s tumor of parotid glands two years before his presentation. He presented with generalized ill-health, body-aches and feeling of further enlargement of his previous swellings at jaw ang...